Vnitr Lek 2012, 58(11):834-838

Rheumatoid arthritis - an independent risk factor for cardiovascular disease

V. Ráček*, P. Němec
Revmatologická ambulance II. interní kliniky Lékařské fakulty MU a FN u sv. Anny Brno, přednosta prof. MUDr. Miroslav Souček, CSc.

Mortality in patients with rheumatoid arthritis compared with general population is increased and approximately one-half of the premature death is due to increased cardiovascular mortality. Traditional cardiovascular risk factors only partly explain increased risk of cardiovascular disease in patients with rheumatoid arthritis. The risk of cardiovascular disease associated with rheumatoid arthritis equals that of diabetes mellitus. Rheumatoid arthritis should be regarded as a strong independent cardiovascular risk factor as diabetes mellitus. The presence of chronic inflammation implicated in pathogenesis of rheumatoid arthritis and atherosclerosis could be the key mechanism that contributes to increased cardiovascular risk. Traditional cardiovascular risk factors reduction combined with tight disease control is recommended to reduce the risk of cardiovascular disease.

Keywords: rheumatoid arthritis; cardiovascular disease; mortality

Received: May 23, 2012; Accepted: August 6, 2012; Published: November 1, 2012  Show citation

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Ráček V, Němec P. Rheumatoid arthritis - an independent risk factor for cardiovascular disease. Vnitr Lek. 2012;58(11):834-838.
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