Vnitr Lek 2006, 52(1):87-88

"Unknown" cause of the onset and recurrence of venous thromboembolism

P. Dulíček1,*, L. Vodičková2, J. Malý1, M. Pecka1, M. Beránek3
1 Oddělení klinické hematologie II. interní kliniky Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. MUDr. J. Malý, CSc.
2 I. interní klinika Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. MUDr. J. Vojáček, DrSc.
3 Oddělení klinické biochemie Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. MUDr. V. Palička, CSc.

We reported the case of 61 years old man with the first episode of massive pulmonary embolism at the age of 54 without the proper explanation of the cause. Thrombocythaemia was manifested after the dismissal from the hospital but the origin of this condition was not clarified. Essential thrombocythaemia was diagnosed after the recurrence of venous thromboembolism and that is the explanation for thrombophilic condition in this patient. The patient is without problems and signs of recurrent venous thromboembolism after the achievement of the complete remission of myeloproliferative disease and well - managed of anticoagulation therapy.

Keywords: venous thromboembolism; pulmonary embolism; essencial thrombocythaemia

Received: November 25, 2005; Accepted: December 23, 2005; Published: January 1, 2006  Show citation

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Dulíček P, Vodičková L, Malý J, Pecka M, Beránek M. "Unknown" cause of the onset and recurrence of venous thromboembolism. Vnitr Lek. 2006;52(1):87-88.
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References

  1. Bertina RM. Molecular risk factors for thrombosis. Thromb Haemost 1999; 82: 601-609. Go to original source... Go to PubMed...
  2. Elliott MA, Tefferi A. Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia. Brit J Haematol 2005; 128: 275-290. Go to original source... Go to PubMed...
  3. Penninga E, Jensen BA, Hansen PB. Anagrelide treatment in 52 patients with chronic myeloproliferative disease. Clin Lab Haematol 2004; 26: 335-340. Go to original source... Go to PubMed...




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