Vnitr Lek 2006, 52(1):40-43

Is the left ventricle enddiastolic pressure pathological in the older population?

M. Vytiska^1,*, P. Kala¹, M. Peciar², O. Boček¹, P. Jeřábek¹, P. Neugebauer¹, M. Poloczek¹, J. Pařenica¹, J. Špinar¹

¹ Interní kardiologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Jindřich Špinar, CSc., FESC

² Stredná zdravotnícka škola, Trenčín, Slovenská republika

Introduction:
The percentage of older population has significantly increased in the recent decades. Morphologic and functional changes of the cardiovascular system go together with ageing. The aim of the study should show the correlation between the age and left ventricular enddiastolic pressure (LVDEP) value.

Methods:
106 patients of the age from 23 to79 years without an organic heart disease and the history of hypertension underwent elective coronary angiography including left ventricle angiography between 1999 and 2002. LVEDP was obtained as an average value from 8 consecutive beats without extrasystoles. According to the relation between increased relative frequency of LVEDP and age patients were divided into two groups: 50 years and older (80 patients) and younger than 50 years (26 patients).

Results:
An average LVEDP value in older population versus younger population was 12.1 ± 5.0 mm Hg vs 8.9 ± 3.4 mm Hg, p < 0.05. Increased LVEDP in yonger population was found in only 11.5 % vs 46.2 % in older group, p < 0.01 and the LVEDP was age dependent, p < 0.05.

Conclusions:
In compliance with about mentioned results we suppose that the age is a factor with impact to LVEDP value. LVEDP values > 12 mm Hg in older population may not be pathological and probably are due to the left ventricle diastolic dysfunction in consequence with ageing.

Keywords: left ventricle enddiastolic pressure (LVDEP)

Received: January 19, 2005; Accepted: October 27, 2005; Published: January 1, 2006  Show citation