Metabolický syndrom, tělesná hmotnost a žilní trombóza - editorial

P. Sucharda

Vnitr Lek 2009, 55(2):89-90  

Midterm results aortic valve replacement with allograft

A. Mokráček, J. Špatenka, H. Pospíšilová, M. Šulda, R. Tesařík, M. Vambera, Š. Šindelářová, F. Toušek, M. Šetina, J. Vojáček, V. Lánská, L. Pešl

Vnitr Lek 2009, 55(2):91-96  

Introduction:Aortic allograft implantation into the aortic position in adults is standard procedure with some controversary. The most popular indication is bacterial endocarditis. We would like to present our midterm results. Results:We implanted 61 allografts in 60 patients (between 10/2002 and 04/2008). Men were 46 (76.8%) and average age was 57 ± 10.76 year. 30 days mortality was 9 people (15.0%, all with bacterial endocarditis). Late mortality 1 man (1.6%). Follow up 1-66 months, average 39.18 SD ± 14.3 months, median 42 months. Conclusion:Implantation of aortic allograft into the aortic position...

Pathophysiology of metabolic acidosis in patients with reduced glomerular filtration rate according to Stewart-Fencl theory

J. Havlín, K. Matoušovic, O. Schück, M. Horáčková, J. Charvát, K. Kotaška, D. Králová

Vnitr Lek 2009, 55(2):97-104  

Aim:Metabolic acidosis is a regular sign of renal insufficiency. Conventional assessment of acid-base balance using Henderson-Hasselbalch equation does not make identification of the cause of metabolic disorders possible as the serum HCO₃^- concentration might only reflect changes to the overall plasma ion spectrum. Therefore, we used the Stewart-Fencl approach that is based on a more detailed physical and chemical analysis and that showed that changes to serum HCO₃^- concentration are closely related to parameters not usually monitored in connection to acid-base balance. Patient group and...

Impact of body weight on the risk of venous thromboembolism

T. Petrovič, T. Koller, J. Payer

Vnitr Lek 2009, 55(2):106-110  

Introduction:Obesity and venous thromboembolism represent a serious medical problem. Material and methods:Their mutual relationship was studied on the group of 124 patients with venous thromboembolism (the study group) and was compared to the group of 124 randomly chosen controls among hospitalized patients matched for age, sex and risk factor profile of venous thromboembolism (the control group). Results:Recorded variables were body weight, presence of arterial hypertension, hypertriglyceridemia and type 2 diabetes or impaired glucose tolerance. We found significantly higher prevalence of obesity - 40 vs 23...

The diurnal variability of blood pressure in patients with hypertension and rheumatoid arthritis

I. Řiháček, P. Fráňa, M. Souček, M. Plachý, B. Kianička

Vnitr Lek 2009, 55(2):111-116  

Background:The patients with rheumatoid arthritis have high prevalence of hypertension and increased risk of cardiovascular morbidity and mortality. Objective:To determine the level of clinical blood pressure (BP) and 24h ambulatory BP in patients with rheumatoid arthritis and hypertension. Analyze the diurnal variability of BP depending on chronic treatment with prednisone, nonsteroidal anti-inflammatory drugs and methotrexate. Group of patients: 60 patients with clinically stable rheumatoid arthritis and treated or newly diagnosed hypertension. 15 male and 45 female, mean age 58 ± 11.3 years. Results:Mean...

Superficial thrombophlebitis - diagnostics and treatment

V. Štvrtinová, A. Dukát, M. Frankovičová, P. Kubisz, P. Labaš, D. Mištuna, J. Radoňák, V. Šefránek, M. Šimaljaková

Vnitr Lek 2009, 55(2):131-135  

Superficial thrombophlebitis (ST) is a common disease, usually considered benign. However, the practice of systemic duplex ultrasonography has revealed a large number of deep-vein thromboses concomitant with ST. In contrast with extensive information on the management of deep vein thrombosis, little is known about the most appropriate treatment of the ST. Systematic duplex ultrasonography investigation has been proposed in the initial management of ST, to detect the presence of any underlying deep vein thrombosis. Because ST may extend into the deep venous system and potentially engender pulmonary embolism, treatment with low-molecular-weight-heparins...

Guidelines for duplex ultrasound exam of limb veins

M. Vítovec, V. Pecháček

Vnitr Lek 2009, 55(2):136-146  

Duplex sonography is the basic method in diagnosing diseases of both the deep and superficial venous system of the limbs. The scope of and the methods used in such exams still display considerable differences from centre to centre. Guidelines have been drawn under the auspices of the Czech Angiological Society, based on state-of-the-art knowledge and in accordance with internationally accepted documents. The guidelines could contribute to unification of the methods used in ultrasound examinations of limb veins.

Aortic valve sparing operations and reconstruction - from anatomy to the long-term results

J. Vojáček, J. Dominik, P. Žáček, M. Tuna, A. Mokráček, J. Harrer

Vnitr Lek 2009, 55(2):117-122  

The implantation of an artificial heart valve (a mechanical valve or a xenograft valve) involves the risk of serious and life-threatening complications for the patient, such as hemorrhagic complications, thromboembolic complications, the risk of endocarditis, the risk of premature degeneration of the xenograft valve, etc. Preserving the patient's own aortic valve eliminates or at least significantly reduces the above complications. On the other hand, it brings about the disadvantage of a technically more demanding surgery and the possible risk of reoperation due to failure of the spared aortic valve. The authors present a comprehensive and up-to-date...

The combination of an ACE inhibitor and a calcium channel blocker is an optimal combination for the treatment of hypertension

J. Widimský

Vnitr Lek 2009, 55(2):123-130  

Combination of drugs from different classes of antihypertensives provides an additional antihypertensive effect thus minimising the probability of adverse effects related to the dose of antihypertensive. Combination therapy is indicated for the following groups of hypertensive patients: (a) all hypertensive patients whose systolic blood pressure exceeds the target systolic blood pressure value by > 20 mm Hg, or whose diastolic blood pressure exceeds the target diastolic blood pressure value by > 10 mm Hg; (b) in patients with diabetes mellitus (because the target values are < 130/80 mm Hg); (c) patients with target organ damage; (d) patients...

Interdigitating dendritic cell sarcoma of low extremitis resistant to high dose chemotherapy BEAM with peripheral blood stem cell transplantation

Z. Adam, K. Veselý, M. Krejčí, L. Pour, F. Fakan, R. Soumarová, J. Neubauer, J. Vaníček, J. Černý, L. Křen, K. Bolčák, L. Šmardová, R. Hájek, J. Mayer

Vnitr Lek 2009, 55(2):147-157  

Interdigitating dendritic cell sarcoma is a rare neoplasm forming part of the group of malignancies derived from histocytic cell line. This nosological unit can be detected only by special immunohistochemical exams. A young man aged 25 found a tumorous swelling in the proximal part of his left crus. The pathological process affected proximal tibial epiphysis and adjacent soft tissues. The first FDG-PET examination performed in the process of determining the clinical stage of the disease showed a high activity in the site of primary tumour (SUV 7.71) and in the site of regional inguinal node (SUV 4.25). Histological examination of a diagnostic excision...

Z odborné literatury

Vnitr Lek 2009, 55(2):160-162  

XVI. česko-slovenská konference o hemostáze a trombóze s mezinárodní účastí

Jaroslav Malý

Vnitr Lek 2009, 55(2):159  

Za docentom MUDr. Tomášom Hildebrandom, CSc.

Miroslav Mydlík

Vnitr Lek 2009, 55(2):158-159