Vnitr Lek 2019, 65(1):19-23 | DOI: 10.36290/vnl.2019.005

Non-celiac gluten/wheat sensitivity: still more questions than answers

Iva Hoffmanová
II. interní klinika 3. LF UK a FN Královské Vinohrady, Praha

Non-celiac gluten/wheat sensitivity (NCG/WS) is a syndrome characterized by intestinal and extra-intestinal symptoms elicited by gluten/wheat ingestion in the persons, who are not affected by celiac disease and wheat allergy. Due to the lack of established biomarkers, the diagnosis of NCG/WS is based on the clinical picture, and it is necessary to validate it in well-defined double-blind, placebo-controlled challenge (The Salerno Experts' Criteria). In the article is discussed a current knowledge of NCG/WS in terms of pathogenesis, diagnosis and treatment.

Keywords: gluten; gluten-related disorders; non-celiac gluten, wheat sensitivity; wheat

Received: February 12, 2018; Accepted: May 14, 2018; Published: January 1, 2019  Show citation

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Hoffmanová I. Non-celiac gluten/wheat sensitivity: still more questions than answers. Vnitr Lek. 2019;65(1):19-23. doi: 10.36290/vnl.2019.005.
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