Vnitr Lek 2024, 70(1):E33-E39 | DOI: 10.36290/vnl.2024.015

Bleeding disorders - overview for clinical practice

Monika Bradáčová, Antonín Hluší

Hemato-onkologická klinika FNOL a LF UP v Olomouci

bleeding disorders are situations manifested clinically by bleeding or an increased risk of bleeding caused by various reasons. In addition to anatomical causes, the main reasons for haemorrhage include impaired haemostasis. From the clinical point of view these are clinical situations in which bleeding is inadequate to inducing stimulus or begins spontaneously and may manifested itself as difficult-to-stop bleeding or prolonged bleeding after operation or after injury. The basis is disturbance of balance due to a quantitative or qualitative disturbance of one of the hemostatic mechanisms, the causes can be combined. The aim of this article is to provide an overview of these conditions in defined scope, highlighting aspects useful in routine clinical practice.

Keywords: bleeding, disseminated intravascular coagulopathy, haemophilia, haemostasis, immune thrombocytopenia, thrombocytopathy, thrombotic thrombocytopenic purpura, von Willebrand disease.

Accepted: February 23, 2024; Published: February 26, 2024  Show citation