Vnitr Lek 2023, 69(8):E19-E25 | DOI: 10.36290/vnl.2023.108

Overlooked upper gastrointestinal tract carcinoma (PEUGIC) - from epidemiology to root cause analysis

Michal Štěpán^{1, 3}, Barbora Pipek^{1, 2, 3, 4}, Patrik Tokoš¹, Petr Fojtík^{1, 4}, Přemysl Falt^{2, 3}

¹ Centrum péče o zažívací trakt, Nemocnice Agel Ostrava-Vítkovice

² II. interní klinika-gastroenterologická a geriatrická FN Olomouc

³ Lékařská fakulta, Univerzita Palackého v Olomouci

⁴ Lékařská fakulta, Ostravská univerzita

PEUGIC (Post Esophagogastroduodenoscopy Upper Gastrointestinal Cancer) is cancer in the upper gastrointestinal tract, which at the time of diagnosis was preceded by gastroscopy in the last 3 years, which did not show this cancer. Its incidence is directly related to the quality of performing upper endoscopy and is therefore a parameter that can be monitored to assess the quality of upper endoscopy at individual endoscopy units. According to available data, PEUGIC accounts for approximately 10 % of all diagnosed cancers of the upper GIT (gastrointestinal tract). It occurs more often in women, at a younger age than common cancers and in patients with higher comorbidities. The most common causes include insufficient quality of endoscopy, insufficient assessment of precancerous conditions and focal lesions during endoscopy and inadequate decisions about further surveillance. In this article, we address the epidemiology of PEUGIC, review the literature, and analyze the main causes leading to it.

Keywords: upper endoscopy, PEUGIC, endoscopy quality.

Accepted: December 5, 2023; Published: December 18, 2023  Show citation