Vnitr Lek 2014, 60(9):772-775

Gliptins: a safe and effective treatment of diabetes mellitus

Jiří Slíva1,2,*, Martin Prázný3
1 Farmakologický ústav 2. LF UK Praha, přednosta doc. MUDr. Martin Votava, Ph.D.
2 Ústav farmakologie 3. LF UK Praha, přednosta prof. MUDr. Jan Bultas, CSc.
3 III. interní klinika 1. LF UK a VFN Praha, přednosta prof. MUDr. Štěpán Svačina, DrSc., MBA

Gliptins are well recognized substances modulating incretin system via inhibition of dipeptidylpeptidase IV. Their efficacy was demonstrated both in monotherapy and in combination with metformin, where they act synergistically. Hence, a better control of diabetes might be assumed. This short article aims to show current trends in their prescription in the Czech Republic.

Keywords: diabetes mellitus; dipeptidylpeptidase IV; gliptins; oral antidiabetics

Received: September 12, 2014; Accepted: September 16, 2014; Published: September 1, 2014  Show citation

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Slíva J, Prázný M. Gliptins: a safe and effective treatment of diabetes mellitus. Vnitr Lek. 2014;60(9):772-775.
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