Vnitr Lek 2001, 47(11):797-801
[Sensitivity of arterial pressure to salt as an independent prognostic factor in hypertension].
- Ustav patologické fyziologie Lékarské fakulty UP, Olomouc.
Klíčová slova: Blood Pressure, drug effects, ; Cardiovascular Diseases, etiology, ; Diuretics, therapeutic use, ; Humans; Hypertension, complications, ; Prognosis; Sodium Chloride, pharmacology,
Considerable evidence has accumulated indicating that sodium sensitivity of blood pressure is an important prognostic factor in hypertension. This review focuses on clinical studies showing close association between sodium sensitivity and cardiovascular diseases such as glomerular capillary hypertension, cerebrovascular events and left ventricular hypertrophy. The mechanisms of therapeutic action of diuretics in salt-sensitive hypertension are discussed.
Keywords: Blood Pressure /drug effects/; Cardiovascular Diseases /etiology/; Diuretics /therapeutic use/; Humans; Hypertension /complications/; Prognosis; Sodium Chloride /pharmacology/
Zveřejněno: 1. listopad 2001 Zobrazit citaci