Vnitr Lek 2000, 46(8):444-446

[Effect of antioxidant therapy on indicators of free radical activity in workers at risk of lead exposure].

V Machartová, J Racek, J Kohout, V Senft, L Trefil
Klinika pracovního LF UK a FN, Plzen.

The authors administered to 36 workers exposed to lead, for four weeks the preparation Prolong which contains vitamin C, vitamin E, beta-carotene, selenium, zinc and chromium and investigated the effect on indicators of free radicals. A statistically significant increase of the following occurred: superoxide dismutase (p < 0.001), glutathione peroxidase (p < 0.01), an increase of the total antioxidant capacity (p < 0.01) and an increase of uricaemia (p < 0.05). Based on these results the authors consider supplementation with antioxidants indicated in workers exposed to lead.

Keywords: Adult; Antioxidants, therapeutic use, ; Free Radicals, metabolism, ; Glutathione Peroxidase, analysis, ; Humans; Lead Poisoning, metabolism, ; Malondialdehyde, analysis, ; Middle Aged; Occupational Diseases, metabolism, ; Superoxide Dismutase, analysis,

Published: August 1, 2000  Show citation

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Machartová V, Racek J, Kohout J, Senft V, Trefil L. [Effect of antioxidant therapy on indicators of free radical activity in workers at risk of lead exposure]. Vnitr Lek. 2000;46(8):444-446.
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