UNLABELLED: Helicobacter pylori is the most frequent cause of antral gastritis type B. Little is known about the affection of the gastric cardia by inflammation associated with H. pylori infection.

OBJECTIVE: Assess the status of morphological changes of the cardia in the presence of H. pylori infection in patients with non-ulcer dyspesia.

METHODS: AND PATIENTS: 251 consecutive dyspeptic patients with H.pylori infection were subjected to endoscopic examination of the upper part of the gastrointestinal tract. Six biopsies were taken (2 antrum, 2, corpus, 2 cardia) for histological (HaE) and microscopic (Giemsa) status, scored according to the Sydney classification.

RESULTS: Chronic inflammation and its activity reached similar values in the antrum and cardia, the difference was not statistically significant (p>0.05). The findings of H.pylori and intestinal metaplasia (IM) were higher in the antrum than in the cardia (p

Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Cardia /microbiology/; Dyspepsia /etiology/; Female; Gastritis /microbiology/; Gastroscopy; Helicobacter Infections /complications/; Helicobacter pylori; Humans; Male; Middle Aged; Pyloric Antrum /microbiology/