Vnitr Lek 1998, 44(2):83-85
[Indicators of effects of free radicals in workers at risk of lead exposure].
- Klinika pracovního lékarství Fakultní nemocnice, Plzen.
Klíčová slova: Adult; Biomarkers, analysis, ; Female; Free Radicals, analysis, ; Humans; Lead Poisoning, diagnosis, ; Male; Middle Aged; Occupational Diseases, diagnosis, ; Risk Factors; Selenium, blood, ; Superoxide Dismutase, blood,
The authors examined indicators of the action of free radicals in 40 workers exposed to the risk of lead (work with lead containing glazing and prints). The lead concentration in the atmosphere did not exceed the highest permissible concentrations and the biological exposure tests as regards lead exposure did not exceed the highest permissible limits. In the examined subjects the authors found a significantly elevated level of superoxide dismutase activity (p < 0.05) which suggests long-term increased peroxide formation. The correlation of the selenium concentration in blood and the period of lead exposure was at the borderline of statistical significance (p = 0.1159). Further investigations will be focused on subjects with symptoms of increased exposure to lead and lead intoxication where the probability of pathological findings is greater.
Keywords: Adult; Biomarkers /analysis/; Female; Free Radicals /analysis/; Humans; Lead Poisoning /diagnosis/; Male; Middle Aged; Occupational Diseases /diagnosis/; Risk Factors; Selenium /blood/; Superoxide Dismutase /blood/
Zveřejněno: 1. únor 1998 Zobrazit citaci