Vnitr Lek 1996, 42(11):784-788

[The role of thromboxane in the pathogenesis of nephropathies].

R Dzúrik, Z Krivosíková, V Spustová
Klinika farmakoterapie Ustavu preventívnej a klinickej medicíny, Bratislava.

Impaired haemostasis, in particular aggregation in renal disease stimulated research of its prevention and treatment. The achieved results are a significant contribution not only to theoretical research but also to its application in nephrological practice. The submitted review presents specific features of nephrological patients ensuing from overproduction of prostaglandins, in particular thromboxane, by renal cells, focused on glomeruli where mesangial and epithelial cells participate in prostaglandin production and where thromboxane is associated with hyperfiltrations, proliferation, aggregation and other processes damaging glomeruli.

Keywords: Animals; Hemostasis; Humans; Kidney, physiology, ; Kidney Diseases, blood, ; Thromboxanes, physiology,

Published: November 1, 1996  Show citation

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Dzúrik R, Krivosíková Z, Spustová V. [The role of thromboxane in the pathogenesis of nephropathies]. Vnitr Lek. 1996;42(11):784-788.
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