Vnitr Lek 1996, 42(10):705-709

[Heparin-induced thrombocytopenia].

P Dulícek, L Chrobák: Oddĕlení klinické hematologie LF UK a FN, Hradec Králové.

Klíčová slova: Anticoagulants, adverse effects, ; Heparin, adverse effects, ; Humans; Thrombocytopenia, chemically induced,

Heparin induced thrombocytopenia (HIT) is the result of platelet activation and it is either nonimmunologically (type I) or immunologically mediated (type II). HIT is the most frequent drug induced immune thrombocytopenia. It is completely different from all other forms of immune thrombocytopenia, because it can be accompanied by serious thromboembolic complication because of its serious clinical consequences must be prompt and very intensive.