Vnitr Lek 1996, 42(10):680-683

[Serum and urinary concentrations of magnesium in patients with chronic heart failure].

V Spisák: Interné oddelenie A, NsP Zilina.

Klíčová slova: Chronic Disease; Female; Heart Failure, metabolism, ; Humans; Magnesium, metabolism, ; Male

Patients with chronic heart failure suffer more frequently, due to cumulation of factors leading to impaired magnesium (Mg) metabolism, from disorders of its concentration in serum and urine. Hypomagnesaemia has a marked (statistically significant) negative impact on the one-the two-year survival of patients. The author examined 57 patients with chronic heart failure. He did not detect hypomagnesaemia in any of them (Mg levels below 0.7 mmol/l). In two instances he found reduced urinary levels of Mg (less than 1 mmol/24 hours). Surprising is the more frequent occurrence of hypermagnesaemia (Mg above 1.0 mmol/l) which has also an adverse (statistically significant) prognostic effect on the one- and two-year survival of these patients. In the discussion the author deals with the effect of individual factors and drugs on Mg concentrations in serum and urine.