Vnitr Lek 1995, 41(6):377-379
[Epstein-Barr virus antibodies: review of results from repeated examinations in 208 hemodialyzed patients].
- Institut klinické a experimentální medicíny, Praha.
Klíčová slova: Antibodies, Viral /analysis/; Antigens, Viral /immunology/; Capsid Proteins; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Herpesvirus 4, Human /immunology/; Humans; Immunoglobulin G /analysis/; Renal Dialysis; Viral Matrix Proteins /immunology/
Latent infection with the Epstein-Bar virus (EBV) is diagnosed as a matter of routine in haemodialyzed patients on the waiting list for renal transplantation by assessment of serum immunoglobulin G (IgG) against the nuclear antigen-1 (EBNA-1). Antibodies against EBNA-1 were detected in 163 of 208 patients (78.27%). Of these 158 entered the investigation already IgG positive against EBNA-1 and five converted later to positivity. Thirty-five of 50 patients who were IgG negative at the onset of the investigation, however, were IgG positive against the capsid antigen (VCA) EBV. Antibodies against EBNA-1 or against VCA were not detected during repeated examinations in the course of one an and a half years in 15 of 208 patients (7.21%).
Zveřejněno: 1. červen 1995 Zobrazit citaci