Vnitr Lek 1994, 40(6):386-390

[New trends in antineoplastic chemotherapy].

P Klener: I. interní klinika 1. LF UK, Praha.

Klíčová slova: Antineoplastic Agents, administration & dosage, ; Humans

The author present some possible ways how to enhance the effectiveness of chemotherapy. In addition to modification of the tactics of chemotherapy it is above all a reduction of the effects of cytostatics and overcoming the resistance to chemotherapy, while the introduction of new drugs is rather rare during the last decade. As to non-traditional ways, a part can be played by more effective prophylaxis of secondaries, induction of cell differentiation, a combination of chemotherapy with biological response modifiers (interferons and cytokines) or treatment with cytokines alone (interleukin-2, tumour necrosis factor).