Vnitr Lek 1994, 40(3):145-150
[Immunophenotyping in chronic B-cell lymphatic leukemia].
- Oddĕlení klinické imunologie a alergologie FN, Hradec Králové.
Klíčová slova: Adult; Aged; Antigens, CD /analysis/; CD5 Antigens; Female; HLA-DR Antigens /analysis/; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell /immunology/; Lymphocyte Subsets; Male; Middle Aged
The authors present the results of immunophenotyping analysis of cells from 67 patients with the diagnosis of B-CLL from group of 393 adults examined by immunophenotyping because of a haematological malignity. Characteristic for B-CLL is the finding of surface molecules HLA DR, B lymphocytic superficial molecules and CD5. Aberrant membrane equipment of B-CLL cells is suggested by the rare absence of some pan B lymphocytic sign. Marked reduction of T lymphocyte ratios, their sub-populations and NK cells is associated with immunodeficiency manifestations which are common in patients with B-CLL.
Zveřejněno: 1. březen 1994 Zobrazit citaci