The authors assessed the frequency of Helicobacter pylori in diabetic patients with gastroduodenal ulceration and non-ulcerative dyspepsia. They evaluated a group of 91 hospitalized type II diabetics which non-ulcerative dyspepsia, endoscopically confirmed ulceration of the duodenal bulbus and gastric ulceration. The control group was formed by 98 hospitalized non-diabetic subjects. Between the two groups there was no difference in the frequency of Helicobacter pylori in non-ulcerative dyspepsia (61.1% as compared with 56.0% in non-diabetics) and gastric ulceration (75.0% as compared with 77.7% in non-diabetics). There is a significantly (p > 0.005) lower incidence of HP infection in diabetics with active duodenal ulceration (46.6%), as compared with non-diabetics (87.5%). The authors assume that active duodenal ulceration in diabetics could be more frequently caused by other factors than Helicobacter pylori.

Keywords: Aged; Diabetes Mellitus, Type 2 /complications/; Dyspepsia /complications/; Female; Helicobacter Infections /complications/; Helicobacter pylori; Humans; Male; Middle Aged; Peptic Ulcer /complications/