Vnitr Lek 1993, 39(2):172-177
[The present status of nitrates in the treatment of ischemic heart disease].
- I. interní klinika FN u sv. Anny, Brno.
Klíčová slova: Coronary Disease, drug therapy, ; Hemodynamics, drug effects, ; Humans; Nitrates, pharmacology,
The authors describe the development of nitrates from substances of the first generation (nitroglycerin and isosorbit dinitrate) to the second generation (isosorbit-5-mononitrate). They explain the mechanism of their action, haemodynamic effects and the problem of nitrate tolerance. Indications of their rational use are given.
Keywords: Coronary Disease /drug therapy/; Hemodynamics /drug effects/; Humans; Nitrates /pharmacology/
Zveřejněno: 1. únor 1993 Zobrazit citaci