Vnitr Lek 1989, 35(11):1106-1110

[Locally produced monoclonal antibodies for the diagnosis of acute leukemias].

V Koza, P Cetkovský

Klíčová slova: Acute Disease; Antibodies, Monoclonal; Humans; Leukemia, diagnosis,

In 35 cases of acute leukaemia in addition to the basic morphological and cytochemical examination immunophenotyping with locally produced monoclonal antibodies from the Institute of Molecular Genetics, Czechoslovak Academy of Sciences, Prague, was made. In 33 instances it proved possible to differentiate the leukaemic cells, two leukaemias were described as non-differentiated. Local antibodies MEM 78, MEM 75, MEM 57, MEM 32, MEM 31, MEM 18 and HL-40 can be considered basic monoclonal antibodies for the diagnosis of acute leukaemia.