Vnitr Lek 1989, 35(4):382-388

[The effect of Biston on cardiac dysrhythmias].

I Lazúr

Klíčová slova: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac, drug therapy, ; Carbamazepine, therapeutic use, ; Female; Humans; Male; Middle Aged

The author treated in 1983-1987 88 patients with different cardiac dysrhythmias with Biston, Spofa. It was most effective in ES arrhythmias. It was also effective in ES arrhythmias grade IV-V according to Lown, even where previously various antiarrhythmic drugs were tested with a small or no effect. After its administration atrial fibrillations receded also; it did not prove possible, however, to convert chronic atrial fibrillation to a sinus rhythm. The drug was less effective in supraventricular paroxysmal tachycardia. With regard to its low toxicity, minimal side effects, availability and price, the author recommends its wider use in antiarrhythmic treatment. The author assumed that it will prove useful also in the prevention of malignant dysrhythmias in postinfarction states.