Vnitr Lek 2010, 56(6):533-540

BRNO Register 2: post-myocardial infarction pharmacotherapy

J. Špinar^1,*, O. Ludka¹, M. Sepši¹, J. Schildberger¹, L. Dušek², J. Jarkovský²

¹ Interní kardiologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Jindřich Špinar, CSc., FESC

² Institut biostatistiky a analýz Lékařské a Přírodovědecké fakulty MU Brno, ředitel doc. RNDr. Ladislav Dušek, Ph.D.

We assessed 850 patients with a history of myocardial infarction > 1 month ago who attended outpatient clinics of the Clinic of Internal Medicine and Cardiology at the Faculty Hospital Brno between 1st September 2009 and 31st December 2009. There were more men (650 vs. 200) and patients under 70 years of age (576 vs. 264) in the cohort. 87.8% of patients experienced one myocardial infarction only and the mean age at the first infarction was 59.0 years in men and 65.5 in women (p < 0.001). 75.8% of patients had been prescribed all recommended pharmacotherapeutic groups according to guidelines (RAAS blockers, beta-blockers, statins, antiagregation agents) and each group individually was used in > 90% of patients. There were no differences between men and women and older and younger patients. ACE inhibitors and statins were not always prescribed in recommended (high) doses. Perindopril was the most frequently prescribed ACE inhibitor and atorvastatin the most frequently prescribed statin. Blood pressure of < 140/90 mm Hg was identified in 60.1% of patients, 75% of men and 65% of women had cholesterol level of < 5 mmol/l and > 50% of patients had cholesterol ≤ 4.5 mmol/l, metabolic syndrome was found in about 1/2 of patients and smoking was admitted by 12.5% of patients.

Keywords: myocardial infarction; ACE inhibitor; statin; blood pressure; cholesterol

Received: May 17, 2010; Published: June 1, 2010  Show citation