Vnitřní lékařství, 2015 (vol. 61), Supplementum 3

Editorial

Úvodní slovo prof. MUDr. Jaroslava Rybky, DrSc., nestora české diabetologie. Význam statistiky v programové péči o nemocné s diabetem

Jaroslav Rybka

Vnitr Lek 2015, 61(Suppl 3):3

Medicine for the future: Clinical foundations firmly anchored through feedback from practice

Milan Kvapil, Richard Češka

Vnitr Lek 2015, 61(Suppl 3):5

The National Health Care Information System of the Czech Republic will significantly enhance the information support of diabetology: editorial

Ladislav Dušek

Vnitr Lek 2015, 61(Suppl 3):8-9

Original articles

The mortality of patients with diabetes mellitus using oral antidiabetic drugs in the Czech Republic decreased over the decade of 2003-2013 and came closer to the population average

Jan Brož, Petr Honěk, Ladislav Dušek, Tomáš Pavlík, Milan Kvapil

Vnitr Lek 2015, 61(Suppl 3):14-20

Introduction:Every year official data is published which describes the care of patients with diabetes mellitus in the Czech Republic. An overall number of individuals with diabetes, the number of newly reported cases and the number of patient deaths is always specified. However this data does not allow us to identify the differences in mortality between the individual cohorts of diabetic patients in relation to therapy. Goal:Comparison of the mortality development in the periods of 2002-2006 and 2010-2013 in a representative sample of the patient population with type 2 diabetes mellitus using oral antidiabetic drugs, kept...

Incidence of amputations among patients with diabetes mellitus in the Czech Republic from 2010 to 2014

Pavlína Piťhová, Petr Honěk, Ladislav Dušek, Tomáš Pavlík, Milan Kvapil

Vnitr Lek 2015, 61(Suppl 3):21-24

Introduction:Information about the incidence of organ-affecting complications of diabetes, including the diabetic foot syndrome, can be obtained from the documents of the Institute of Health Information in the Czech Republic. Goal:Assessment of the development of high amputations and minor surgical procedures on the lower limb from 2010 to 2014 in a representative sample of the population of patients with DM kept in the General Health Insurance Company of the Czech Republic database. Methodology:We identified all individuals in the VZP database who had a record of DM diagnosis (E10 - E16 based on ICD 10) or...

Analysis of the development of metformin and sulfonylurea prescriptions in the Czech Republic

Denisa Janíčková-Žďárská, Petr Honěk, Ladislav Dušek, Tomáš Pavlík, Milan Kvapil

Vnitr Lek 2015, 61(Suppl 3):25-29

Introduction:In the Czech Republic, patients with diabetes mellitus (DM) are followed and treated predominantly by specialists (approx. 80% at a specialist diabetology clinic), a minor part by general practitioners (up to 20%). Long-term development of the changes in prescribing metformin and sulfonylurea in the Czech Republic and its concordance with recommended procedures has not been evaluated until now. Goal:Comparison of the development of metformin (MET) and sulfonylurea (SU) prescriptions in the period of 2002-2006 with that of 2010-2014 in a representative sample of the patient population with DM kept in the database...

Hypolipidemic and antihypertensive therapy in diabetic patients in the Czech Republic: notes on the VZP (General Health Insurance Company) Data

Michaela Šnejdrlová, Richard Češka, Denisa Janíčková-Žďárská, Petr Honěk, Pavel Dušek, Tomáš Pavlík, Milan Kvapil

Vnitr Lek 2015, 61(Suppl 3):30-37

Diabetes mellitus and in particular type 2 diabetes mellitus is one of the most important risk factors of cardiovascular disease. To influence cardiovascular risk there is enormous important not only positive influence of glycemia, but also the treatment of diabetic dyslipidemia and hypertension. The present work provides an analysis of lipid-lowering and antihypertensive therapy for all diabetics registered with General Health Insurance Company in the period 2010-2013. In this time 866 570 patients with diabetes mellitus registered with General Health Insurance Company were treated, the majority of them were diabetics independent on insulin. Approximately...

Monitoring of diabetes compensation in patients treated with an insulin pump in the Czech Republic

Zdeněk Rušavý, Petr Honěk, Ladislav Dušek, Tomáš Pavlík, Denisa Janíčková-Žďárská, Milan Kvapil

Vnitr Lek 2015, 61(Suppl 3):39-43

Introduction:Insulin pump treatment (IP) is one of the ways of intensive insulin therapy, designed preferentially for patients with type 1 diabetes. The price of the treatment is higher than that of the conventional basal-bolus and insulin regimens using repeated insulin application with a dose selector. Goal:Quality assessment of IP therapy monitoring in patients with DM in a representative sample of the patient population with DM kept in the database of the General Health Insurance Company of the Czech Republic (VZP) which provided health care coverage for 63% of Czech population in 2014. Methodology: We identified all individuals...

The PROROK project results after 6 months of intervention (Prospective observation project focusing on the relevance of the difference between fasting blood glucose levels and postprandial blood glucose for estimation of success of type 2 diabetes therapy)

Denisa Janíčková-Žďárská, Pavlína Piťhová, Tomáš Pavlík, Milan Kvapil

Vnitr Lek 2015, 61(Suppl 3):44-49

Introduction:The PROROK project (Prospective observation project focusing on the relevance of the difference between fasting and postprandial blood glucose levels for the estimation of success of type 2 diabetes therapy) had a character of non-interventional, prospective, multicentric observation study lasting 6 months, whose goal was to quantify the rele-vance of the difference between fasting and postprandial blood glucose levels to the success of the treatment with GLP1 receptor agonists, resp. the treatment with basal, premixed insulin, or a combination of basal-bolus insulin. Physicians chose a therapy for patients with insufficiently...

Clinical and economic benefits of the new antidiabetic drugs in the Czech Republic

Tomáš Doležal, Klára Kruntorádová

Vnitr Lek 2015, 61(Suppl 3):50-53

Goal:Description of efficiency, safety and cost-effectiveness of the therapy with new antidiabetics from the incretins group for the patients whose treatment with DPP4 inhibitors and GLP1 receptor agonists respectively, commenced based on the real data from the routine clinical practice in the Czech Republic. Methodology:Collection of clinical data before the commencement of treatment and in the following 12 months. The following data was collected for all patients: demographic data, time elapsed from diagnosis, body weight, BMI, HbA_1c, systolic and diastolic blood pressure, total cholesterol, LDL-cholesterol, HDL-cholesterol...

Reviews

Realistic possibilities of using data sources in quality assessment of care of patients with diabetes in the Czech Republic: National Diabetes Information System

Milan Kvapil

Vnitr Lek 2015, 61(Suppl 3):10-13

Diabetes mellitus is a serious health and economic problem of our time. Therapy is primarily perceived as prevention of the late complications of diabetes. Most pharmacoeconomic analyses state that the cost associated with the therapy of diabetes mellitus is largely spent on the therapy of its complications. The project of the National Diabetes Information System is based on the essential principle of automated collection of data which is available in digital form in the Czech Republic and which describes the quality and quantity of the care provided for patients with diabetes mellitus and its results. Benefits of the posited National Diabetes Information...