Hyponatremie - biomarker nebo mediátor? V každém případě výzva! - editorial

M. Matějovič

Vnitr Lek 2013, 59(10):869-871  

Léčebný přístup k vysoce rizikové chronické lymfocytární leukemii: alogenní transplantace krvetvorných buněk je jedinou šancí na trvalé vyléčení - editorial

L. Smolej

Vnitr Lek 2013, 59(10):872-873  

Infekční endokarditida u intravenózních toxikomanů - editorial

P. Gregor

Vnitr Lek 2013, 59(10):874-875  

Prevalence of hyponatremia in patients on department of internal medicine

M. Rudnay, I. Lazúrová

Vnitr Lek 2013, 59(10):876-879  

Introduction:Hyponatremia is the most common electrolyte disorder detected by biochemical laboratories in the present time and interest about it increases because of new informations about its consequences. Aim:Objective of our work was to determine the prevalence of hyponatremia in patients hospitalized at clinic of internal medicine and to analyze its most common causes. Patients and results:The total number of hospitalized patients for a period of 6 months was 1,203. Severe hyponatremia, i.e. S-Na < 130 mmol/l was detected in 83 cases, i.e. 6.9% of all patients. 14 patients, i.e. 1.15% have more severe...

The impact of a 14-day regular physical exercise regime on the concentration of the classes and sub-classes of lipoprotein particles in young subjects with a sedentary lifestyle

P. Sabaka, A. Dukát, S. Oravec, L. Mistríková, D. Baláž, M. Bendžala, Ľ. Gašpar

Vnitr Lek 2013, 59(10):880-886  

Recommendations from the cardiological professional companies working in the area of primary prevention of cardiovascular diseases put an emphasis on regular aerobic physical activity. Its positive effect on both cardiovascular and overall mortality has repeatedly been proven by the observations of prospective and cross-sectional epidemiological studies. One of the possible explanations of this positive effect is a change in the concentration of lipoprotein classes and their sub-classes, which is expressed as a change in their average size. In a group of young healthy men and women with a sedentary lifestyle we observed the effect of medium intensive...

Doporučení pro diagnostiku a léčbu onemocnění štítné žlázy v těhotenství a pro ženy s poruchou fertility

J. Horáček, J. Jiskra, Z. Límanová, D. Springer, V. Zamrazil

Vnitr Lek 2013, 59(10):909-931  

Management of dyslipidaemias - present and future. Guidelines of the Angiology Section of the Slovak Medical Chamber (2013)

P. Gavorník, A. Dukát, Ľ. Gašpar

Vnitr Lek 2013, 59(10):932-938  

Aim:The aim of Guidelines of the Angiology Section of the Slovak Medical Chamber is to address a last European guidelines for the management of dyslipidaemias, as well as results in evidence-based-medicine (EBM) in order to assess their contribution to our expanding knowledge on reducing of residual organovascular risk. Discussion:Lipid metabolism can be disturbed in different ways, leading to changes in plasma lipoprotein function and/or levels. This by itself and through interaction with other vascular risk factors and endothelial dysfunction may affect the development of atherosclerosis and other vascular diseases. Therefore,...

Ultra-high-risk chronic lymphocytic leukemia - characteristics and treatment options

D. Lysák, P. Jindra

Vnitr Lek 2013, 59(10):887-894  

Chronic lymphocytic leukemia (CLL) is the most common form adult leukemia in western world. The disease is typically characterized by heterogeneous clinical behavior ranging from indolent course to rapidly progressive disease. Using clinical and biological factors we can stratify patients with CLL and prospectively identify those who can be expected unfavorable course. There is a special group known as ultra high-risk chronic lymphocytic leukemia with an extremely poor prognosis. These are about 10-15% of all patients with CLL. They do not respond to standard treatment and their survival is short with a median of 2-3 years. For high-risk patients are...

Methods of skin microcirculation assessment

J. Tomešová, J. Gruberová, P. Brož, S. Lacigová, M. Krčma, Z. Rušavý

Vnitr Lek 2013, 59(10):895-902  

Microcirculation plays an important role in pathophysiology of a number of severe diseases. At present there exist many techniques that enable evaluation of microvascular perfusion. Some of them found their scientific and clinical use even in the Czech Republic. In last decade, articles referring about individual methods can be found even on the pages of Vnitřní lékařství journal. The aim of this work is to provide a comprehensive overview of methods that have been used for examination of the microcirculation to date. After a short review of the anatomy and physiology of the microcirculation, the article provides synopsis of the theoretical and practical...

The current approach to the treatment of the patients with metastatic colorectal cancer

J. Halámková, J. Tomášek, S. Rybníčková, D. Adámková Krákorová, B. Bencsiková, I. Kiss

Vnitr Lek 2013, 59(10):903-908  

Colorectal cancer is one of the most common malignant tumors. Despite the constant promotion of prevention remains around 20-30% of cases diagnosed in the metastatic stage and approximately 50-60% of patients developed the late dissemination. In 80-90% of them we can find already unresectable metastases. Although surgical treatment is basic modality of therapy, with using modern targeted therapy in combination with chemotherapy we can achieve long-term complete remission in the cases of advanced tumor and we can significantly prolonged the life of patients with this disease now. About 40-50% patients in advanced stages who underwent metastasectomy...

Tricuspid valve infective endocarditis in intravenous drug abuser

O. Rataj, L. Martinkovičová, M. Šetina

Vnitr Lek 2013, 59(10):939-942  

Infective endocarditis can be divided from practical point of view into native valve endocarditis and prosthetic valve endocarditis. With regard to aquired endocarditis, endocarditis in intravenous drug abusers can be separetly differentiated. Echocardiography and microbiological cultures are essential for diagnosis. Treatment consists of antibiotic therapy and often surgical procedure is required. We present a case report of an intravenous drug abuser with a tricuspid valve endocarditis, successfully treated with antibiotic therapy and a following surgical valve repair.

Arachnoid cysts, arachnoidální cysty mozku a míchy (Z odborné literatury)

prof. MUDr. Vladimír Smrčka, CSc.

Vnitr Lek 2013, 59(10)

Cestovní zpráva ESIM 2013, Cappadocia, Turecko (Zprávy z odborných akcí)

MUDr. Zuzana Šomlóová, Ph.D.

Vnitr Lek 2013, 59(10)