Povrchová tromboflebitida, neprávem podceňovaná choroba - je čas změnit názor? - editorial

D. Karetová

Vnitr Lek 2012, 58(9):625-626  

Splenektomie a sepse: pacienti musí být informováni o riziku, musí být vakcinováni a v určitých případech užívat profylakticky antibiotika - editorial

Z. Ráčil

Vnitr Lek 2012, 58(9):627-628  

Je možné snížit četnost závažných infekcí u pacientů po splenektomii? - editorial

L. Rožnovský

Vnitr Lek 2012, 58(9):629-630  

Leptospiróza - editorial

P. Husa

Vnitr Lek 2012, 58(9):631-632  

A comparison of two methods of long-term external ECG telemonitoring in patients after ablation for atrial fibrillation

J. Chovančík, V. Bulková, M. Fiala, J. Gandalovičová, Š. Královec, R. Neuwirth, H. Tolaszová, O. Jiravský, J. Brada, J. Januška

Vnitr Lek 2012, 58(9):633-639  

Aim:The aim of the study was to compare two methods of long-term ECG monitoring after atrial fibrillation (AF) ablation. Methods:The study included 279 patients with paroxysmal (n = 163) or persistent (n = 116) AF, who were followed up for 1 year after the first catheter ablation for AF. All patients were provided with episodic ECG recorder for 1 year and instructed to send at least 2 random ECG recordings per day and whenever they sensed symptoms. They were also provided with external loop recorder for 2-3 weeks at 6 and 12 months to enable more continuous ECG monitoring. Results:At the end of 39 ± 12...

Regular exercise training decreases asymmetric dimethylarginine after kidney transplantation

V. Teplan, A. Mahrová, K. Švagrová, J. Racek, R. Gürlich, V. Teplan jr, L. Šenolt, M. Štollová

Vnitr Lek 2012, 58(9):640-646  

Background:Levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine are elevated in patients undergoing kidney transplantation and may contribute to vascular complications. In this study we tested the hypothesis that elevated asymmetric dimethylarginine can be reduced in patients after kidney transplantation by early regular physical exercise. Selected cytokines and metabolic parameters were also analysed. Methods:Plasma samples for analysis of asymmetric dimethylarginine, adiponectin, leptin, soluble leptin receptor, resistin, visfatin, CRP, TNFα and selected metabolic parameters were obtained...

Peripartal life-threatening hemorrhage - interdisciplinary consensus opinion

J. Kvasnička, M. Balík, T. Binder, J. Blatný, J. Bláha, K. Cvachovec, V. Černý, P. Dulíček, J. Feyereisl, Z. Hájek, P. Janků, J. Malý, A. Měchurová, A. Pařízek, M. Penka, M. Procházka, A. Roztočil, V. Řeháček, D. Seidlová, P. Ševčík, J. Valenta, P. Ventruba

Vnitr Lek 2012, 58(9):661-664  

22 experts from the fields of gynecology and obstetrics, anesthesiology and resuscitation, intensive care, hematology and transfusion medicine has developed recommendations for diagnosis and procedure for life-threatening peripartum haemorrhage, which is still one of the most common causes of maternal mortality in childbirth. This guidelines, which is valid for the Czech Republic, supported by a total of 10 professional medical societies. There are based on new knowledge applicable at this time and is focused mainly on eliminating the most common causes of bleeding during delivery and prevention of haemorrhagic shock.

Superficial thrombophlebitis, unjustly underestimated disease - has the time come to change our view?

J. Hirmerová

Vnitr Lek 2012, 58(9):647-653  

Superficial thrombophlebites represent a very heterogeneous group of diseases which is caused by the difference between two basic forms of ST - varicophlebitis and thrombophlebitis of a "healthy" vein, as well as by other factors - the ratio of thrombotic and inflammatory process, the location and extent of thrombosis in superficial venous system, the distance from deep venous system, the stage of venous insufficiency and the general thrombotic risk of a patient. ST shares many common features with deep vein thrombosis (clinical risk factors, thrombophilic disorders), both diseases often coincide or follow one another. Some authors suggest considering...

Drug compliance - a pitfall of therapy of rheumatoid arthritis?

L. Hromádková, T. Soukup, J. Vlček

Vnitr Lek 2012, 58(9):654-658  

Drug compliance is one of the conditions for effective treatment of various chronic diseases, including rheumatoid arthritis as well. This disease is characterized by a variable course, remissions and relapses, and also by specific treatment. The character of this illness and used medications may represent a risk in terms of non-compliance. As in other chronic diseases, scientists engage in identifying of the compliance rate for many years and the aim of this work is to summarize the state of knowledge in the field of drug compliance in rheumatoid arthritis.

Warning about risk of invasive infections in splenectomized patients. Experiences from University Hospital Brno, Czech Republic, in 2011

P. Polák, M. Freibergerová, P. Husa, P. Šlesinger, R. Svoboda, J. Stašek, L. Frola, C. Macháček

Vnitr Lek 2012, 58(9):665-667  

Syndrome of fulminant sepsis in splenectomized (overwhelming postsplenectomy infection - OPSI) is feared and often fatal infectious complication in patients after splenectomy. The risk of syndrome of fulminant sepsis in splenectomized in these persons persists lifelong and doesn't diminish during the time. Etiologically, encapsulated bacterias like Streptococcus pneumoniae, Haemophilus influenzae group b and Neisseria meningitidis are involved. As the mortality of syndrome of fulminant sepsis in splenectomized is very high, it is indispensable to educate and vaccinate persons in risk. The authors present case reports of three splenectomized patients...

Morbus Weil - a case study and principles

P. Majdák, I. Drexlerová, M. Staňáková, P. Malinjak, J. Melicherík

Vnitr Lek 2012, 58(9):668-673  

We present a case of a 66 years old man without significant medical history who was admitted to a geriatric department of a local hospital for a critical clinical state with severe icterus (billirubin 368 μmol/l), acute renal failure (urea 48 mmol/l, creatinine 714 μmol/l) and severe thrombocytopaenia. When the patient's son completed his personal history on the 4^th day of hospitalization reporting that the patient had worked in a pub flooded during local floods, we also considered leptospirosis as a potential cause of his current state. Parenteral penicillin antibiotics (amoxicillin + clavulanate) were prescribed and comprehensive...

Heart tumor manifesting as a sudden cardiac death

L. Koten, P. Salajka

Vnitr Lek 2012, 58(9):674-678  

Cardiac tumors are rare. They can be divided into primary and secondary. Primary tumors are benign or malignant. The diagnostics is based on imaging techniques. Therapy is surgical on the first place, followed by chemotherapy and radiotherapy in case of malignant tumors. Prognosis of benign tumors is favourable. We present a case report of a patient dying suddenly after hospital admission on for malignant ventricular arrhythmia. Gradually we revealed a nehodgkin lymphoma infiltration of the heart as the structural fundament of this arrhythmia.

Our experience in treatment of multicentric plasma-cell Castleman disease associated with vasculitis manifestations - case report and literature review

P. Szturz, Z. Adam, M. Moulis, L. Šmardová, M. Klincová, R. Šlaisová, R. Koukalová, Z. Řehák, P. Volfová, J. Chovancová, O. Stehlíková, J. Mayer

Vnitr Lek 2012, 58(9):679-690  

Castleman disease is a rare idiopathic non-neoplastic lymphoproliferative disorder with 2 clinical (unicentric and multicentric) and 3 histomorphological (hyaline-vascular, plasma-cell and mixed) forms identified. The case report given here describes the 3-year experience with therapy in a patient, male born 1961, diagnosed with multicentric plasma-cell Castleman disease (HIV and HHV-8 negative) with the finding of generalized lymphadenopathy and splenomegaly. During first line treatment (R-CHOP: rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone, 3 cycles in total, 12/2008-2/2009) the development of bilateral upper and lower limb edemas...

Hyperventilation echocardiography in spastic angina pectoris diagnosing

M. Kaletová, D. Marek, E. Sovová, I. Mejtská, M. Táborský

Vnitr Lek 2012, 58(9):691-696  

Hyperventilation echocardiography is an established diagnostic test in patients with suspected variant angina pectoris. It has got sufficient sensitivity (60-80%) and specificity (85-100%). Positive hyperventilation test is rarely found, which relates to low prevalence of variant angina. The diagnostic yield of the test depends on the population selected for testing: positive result can be expected in patients with a history of typical burning chest pain, ST segment elevation/depression and/or inversions of U wave during the chest pain episode, arrhythmias related to the chest pain, coronary artery stenosis less than 50% of artery diameter, multi-vessel...

Aktuální poznatky o nových perorálních antikoagulanciích z Kongresu Evropské kardiologické společnosti v Mnichově (25.-29. 8. 2012)

J. Kvasnička

Vnitr Lek 2012, 58(9):697-700  

Prestižní cena pro jihočeské kardiocentrum

Jana Tlapáková

Vnitr Lek 2012, 58(9):704-705  

XIX. kongres České internistické společnosti ČLS J. E. Purkyně. Brno, 24.-27. 10. 2012 (Postery)

Vnitr Lek 2012, 58(9)

XIX. kongres České internistické společnosti ČLS J. E. Purkyně. Brno, 24.-27. 10. 2012 (Přednášky, volná sdělení)

Vnitr Lek 2012, 58(9)

XIX. kongres České internistické společnosti ČLS J. E. Purkyně. Brno, 24.-27. 10. 2012 (Sesterská sekce)

Vnitr Lek 2012, 58(9)

Zpráva o konání XVI. česko-slovenského hematologického a transfuziologického sjezdu a XIII. česko-slovenské konference laboratorní hematologie

M. Penka

Vnitr Lek 2012, 58(9):701-702