Úvodník

Richard Češka

Vnitr Lek 2007, 53(9):917  

Výsledek celotělového FDG-PET vyšetření predikuje osud nemocných s difuzním velkobuněčným lymfomem - editorial

M. Klabusay

Vnitr Lek 2007, 53(9):918  

Jaká je role katetrové ablace A-V junkce a trvalé kardiostimulace v době, kdy lze fibrilaci síní všech forem léčit selektivní katetrovou ablací? - editorial

M. Fiala

Vnitr Lek 2007, 53(9):919-922  

Léčba fibrilace síní v době katetrové ablace - editorial

R. Lábrová

Vnitr Lek 2007, 53(9):923-924  

Možnosti imunomodulační terapie u kriticky nemocných - lepší diagnostika znamená účinnější léčbu - editorial

M. Průcha

Vnitr Lek 2007, 53(9):925-927  

Tuková buňka stále plodnější - editorial

P. Sucharda

Vnitr Lek 2007, 53(9):928-929  

Únavový syndrom v onkologii - editorial

P. Vodvářka

Vnitr Lek 2007, 53(9):930  

Invazivní houbové infekce u nemocných po transplantaci kmenových buněk krvetvorby: vývoj v diagnostice, prevenci a léčbě v posledním desetiletí - editorial

P. Cetkovský

Vnitr Lek 2007, 53(9):931-933  

Inkretinová strategie léčby diabetes mellitus 2. typu - DPP-IV - editorial

J. Rybka

Vnitr Lek 2007, 53(9):934-935  

The outcome of whole-body FDG-PET examination predicts the future of patients with diffuse large-cell lymphoma in the use of both intermediary staging and at the end of standard chemotherapy

M. Trněný, O. Bělohlávek, J. Kořen, R. Pytlík, J. Šálková, P. Klener

Vnitr Lek 2007, 53(9):936-941  

Aim:Response to the therapy is one of the most valuable prognostic factors. The response evaluation is performed by computer tomography as a standard tool. The introduction of FDG-PET whole body imaging allows to discriminate viable tumor and fibrotic changes in structural abnormalities. Methods:We have performed retrospective analysis of 96 patients with diagnosis of diffuse large B-cell lymphoma (1999-2004) who were treated by anthracyclin based chemotherapy and FDG-PET was performed as a part of intermediate restaging (after 2nd-4th cycle, 69 patients) or/and at the end of standard chemotherapy (68 patients). Results:The...

Long-term monitoring of patients with clinical symptoms of upper gastrointestinal tract bleeding with a negative endoscopy result

E. Machytka, J. Ehrmann, P. Svoboda, P. Klvaňa, A. Martínek, P. Vávra

Vnitr Lek 2007, 53(9):942-946  

The authors present the results of a long-term monitoring of patients who presented with clinical signs of bleeding from the upper gastrointestinal tract (GIT) but totally negative endoscopy results on admission. Retrospective-prospective analysis of acute endoscopies in patients with clinical signs of bleeding from the upper gastrointestinal tract performed in the Endoscopy Centre of the Ostrava Teaching Hospital from 2002 to 2005, long term monitoring of the sample with negative results on admission. A total of 133 patients, i.e. 16.3 % of all acute procedures, with no source of bleeding detected in the first endoscopy. 26.4 % of wrong indications....

Early haemodynamic changes after radiofrequency ablation of the atrioventricular junction

S. Mišíková, B. Stančák, E. Komanová

Vnitr Lek 2007, 53(9):947-953  

Introduction:The effect of radiofrequency ablation of the atrioventricular junction may be accompanied by undesired effect of right ventricular stimulation. The objective of the study was to evaluate early haemodynamic effects of catheter ablation in patients with permanent atrial fibrillation resistant to pharmacotherapy. Method:The study included 19 patients aged 66.9 ± ± 12.4 years on an average. Depending on the basal ejection fraction (EF), we divided the patients in to two groups (the 1st group patients had EF less than 50 %, the 2nd group patients had EF equal to 50 % or higher). The patients were underwent...

Immodin in the treatment of immunoparalysis in intensive care patients

V. Šrámek, L. Dadák, M. Štouračová, P. Štětka, L. Komolíková, P. Kuklínek

Vnitr Lek 2007, 53(9):954-959  

Objective:The objective of the study was to evaluate the effect of administration of the immunoregulating preparation Immodin (Sevapharma, CZ) to influence immunoparalysis in intensive care unit patients. Method:A double blind, randomised clinical study was designed for the above purpose. The patients in whom immunoparalysis was detected during monitoring (CD14+ HLA-DR+ ≤ 40 %) were randomised for the administration of Immodin (IM) or placebo (PL); the treatment lasted for 5 days. 45 (25 % of all monitored) patients - the men/women ratio being 29/16, 60 (54; 65) years of age - were enrolled in the study (of which 25 IM...

Serum level of retinol-binding protein 4 in obese patients with insulin resistance and in patients with type 2 diabetes treated with metformin

M. Tajtáková, Z. Semanová, G. Ivančová, J. Petrovičová, V. Doničová, E. Žemberová

Vnitr Lek 2007, 53(9):960-963  

Objective:Is there a difference between the retinol-binding protein 4 (RBP4) levels in obese patients with insulin resistance (IR) without diabetes, in obese patients with type 2 diabetes mellitus (DM2T) treated with metformin and in nonobese healthy individuals? Method:28 obese individuals with insulin resistance, 11 type 2 diabetes patients treated with metformin and 17 control individuals were examined for serum level of retinol-binding protein 4 using the RIA method. The results were compared within the groups and RBP4 was correlated with insulin in the IR group and the control group. Outcome:The highest...

QT dynamicity in risk stratification in patients after myocardial infarction

T. Novotný, M. Šišáková, A. Floriánová, O. Toman, I. Dohnalová, M. Poloczek, P. Kala, I. Kyselová, L. Dostálová, P. Vít, J. Špinar

Vnitr Lek 2007, 53(9):964-967  

Background:Ventricular repolarization abnormalities are associated with increased risk of sudden cardiac death in patients after myocardial infarction. The aim of this study is to assess QT dynamicity - QT/RR relationship - in patients after myocardial infarction and its contribution to risk stratification of sudden cardiac death. Methods:In a group of patients with diagnosis of acute myocardial infarction a long term ECG recording was performed 48-72 hours after myocardial infarction (MARS Unity Workstation, GE Medical Information Technologies). Patients with unstable circulation, artificial pulmonary ventilation, left bundle...

Endoscopic findings in upper gastrointestinal tract in patients with liver cirrhosis

P. Svoboda, J. Ehrmann, P. Klvaňa, E. Machytka, M. Rydlo, V. Hrabovský

Vnitr Lek 2007, 53(9):968-971  

151 patients suffering from the cirrhosis of the liver underwent a prospective endoscopic examination of the upper digestive tract. The most frequent diagnoses in the group with the cirrhosis of the liver included oesophagus varices (64.9 %), portal hypertension gastropathy (45,7 %) and the peptic ulcer of the gastroduodenum (25.8 %). A normal diagnosis in the endoscopy of the upper digestive tract was found only in 8.6 %. Other diagnoses comprised reflux oesophagitis (13.2 %), diaphragm hiatus hernia (12.6 %), duodenogastric reflux (8.6 %), gastric antrum erosion (4.6 %), aphthic gastropathy (3.3 %), rhagades of the cardium (2 %), gastric polyp (1.3...

Intraabdominal hypertension at intensive care units

P. Szturz, V. Chýlek, R. Kula

Vnitr Lek 2007, 53(9):972-978  

Intraabdominal hypertension is frequently observed both in surgical and non-surgical patients hospitalised at intensive care units. This clinical syndrome of multifactorial etiology is characterised by increased intraabdominal tension with subsequent development of organ dysfunctions. It is reflected in impaired cardiovascular, pulmonary, renal, splanchnic and neurological functions which improve after the abdominal decompression. Patients with intraabdominal hypertension can be relatively easily identified by measuring tension in the bladder the primary purpose of which is early detection of clinically less severe stages and also the detection of...

Chronic fatigue syndrome in cancer patients. Diagnostic and treatment options.

F. Jedlička, L. Elbl, I. Vášová, I. Tomášková, J. Vorlíček, J. Špinar

Vnitr Lek 2007, 53(9):979-985  

Fatigue is the most frequent symptom accompanying a cancer disease and its treatment according to the visual analogue scale. Fatigue is reported by as many as 100 % of patients in the course of cancer treatment and still by 40 to 70 % of patients one year after the treatment has finished. This symptom has become known under the designation of "cancer-related fatigue" in the English language literature on the subject. The knowledge of the causes and mechanisms of fatigue is relatively limited. Based on practical guidelines, an algorithm has been used to detect, evaluate and influence by treatment the syndrome of fatigue caused by a cancer disease. Research...

Current applications of robotic heart surgery

M. Šetina, J. Veselka, A. Mokráček, I. Vaněk

Vnitr Lek 2007, 53(9):986-989  

Objective:The objective of the article is to describe the history, development and current state of robotic heart surgery. Introduction:Robotic heart surgery is a new technology which has recorded dramatic growth in recent years. This is because of the effort to develop, in all fields of surgery, new and minimally invasive methods and to reduce surgical stress. Method:Overview of the relevant literature dealing with the history and development of robotic surgery, with a focus on heart surgery. Results:The number of centres using a robot in clinical practice is growing fast. After a slow start,...

Early diagnosis of invasive fungal infections in hematooncological patients by serological methods

Z. Ráčil, I. Kocmanová, B. Wagnerová, M. Lengerová, J. Mayer

Vnitr Lek 2007, 53(9):990-999  

Invasive fungal infections have become one of the major causes of morbidity and mortality in hematooncological patients over the past 2 decades. Even there is an increasing incidence of invasive fungal infections caused by rare filamentous fungi, the majority of infections are caused by Candida sp. and especially Aspergillus sp. Early diagnosis and prompt initiation of antifungal treatment are leading factors influencing prognosis of patients with invasive fungal infection. Important advances in the field of early diagnosis of invasive fungal infections have been realized over the last years. Beside of new radiological methods the major...

Primary aldosteronism

A. Tokárčiková

Vnitr Lek 2007, 53(9):1000-1002  

Primary aldosteronism is caused by autonomous overproduction of aldosteron in the adrenocortical cells of zona glomerulosa. It is the most frequent form of endocrine hypertension. The morphologic base of this disorder are tumorous, or hyperplastic changes of the adrenal gland. Syndrome is divided into more well-defined pathogenetic forms. Therapy that we use is conservative, or surgical. Success of treatment depends on the correct diagnosis of pathogenetic form and on the duration of hypertension.

Incretin strategy in the treatment of type 2 diabetes mellitus - DPPIV

J. Perušičová

Vnitr Lek 2007, 53(9):1005-1009  

Administration of GLP-1 analogue resistant to DPPIV or therapeutic inhibition of the enzymes, allowing for an increase in the levels of GLP-1, are the very new approaches to the treatment of type 2 diabetes mellitus. Incretin therapy has an immense potential of improving unsatisfactory compensation in diabetic patients thus reducing the risk of manifestation of all arterial complications. Low fasting circulating levels of GLP-1 (and also GIP) grow rapidly after eating and are subsequently degraded to inactive forms by dipeptidyl peptidases IV (DPPIV). DPPIV are enzymes widely present in the body which proteolytically degrade GLP-1 and GIP (as well...

Novák Z, Chrastina J, Říha I. Atlas of Endoscopic Neurosurgery. Atlas endoskopické neurochirurgie

Jan Hemza

Vnitr Lek 2007, 53(9):1014  

Prof. MUDr. Jaromír Hradec, CSc., šedesátníkem

Štěpán Svačina, Petr Sucharda

Vnitr Lek 2007, 53(9):1012  

Vzpomínka na emeritního primáře interního oddělení Krajské nemocnice T. Bati, a.s., ve Zlíně, prim. MUDr. Rostislava Lukaštíka

Jiří Bakala

Vnitr Lek 2007, 53(9):1013  

5. medzinárodný kongres o výskume uremického syndrómu a uremickej toxicity, 7. nefrologická konferencia baltických štátov

M. Mydlík, K. Derzsiová

Vnitr Lek 2007, 53(9):1010-1011