[Percutaneous transluminal angioplasty of the renal artery in transplanted kidneys].

D Krajícková, J H Peregrin, J Stríbrná, A Belán, S Vítko

Vnitr Lek 1997, 43(12):775-780

UNLABELLED: The objective of the work was to evaluate the contribution of percutaneous transluminal angioplasty (PTA) to treatment of hypertension and the graft function of a transplanted kidney. Angioplasty of the graft artery was performed in 39 patients. Technical success rate: 85%.COMPLICATIONS: 13%--in particular during the first years after introduction of the method. Twenty seven patients were followed up on a long-term basis. Changes of the median arterial pressure (MAP) were evaluated as well as glomerular filtration (GF) assessed by creatinine clearance. Mean values: [table: see text] A statistically significant (p < 0.01) reduction...

[Personal experience in the diagnosis and monitoring of therapy in metabolic disorders with risk of crystallization in patients with recurrent urolithiasis].

D Stejskal, J Bártek, J Hrebícek, J Bána, F Záťura, P Mohapl, R Terber

Vnitr Lek 1997, 43(12):781-786

A ten-year experience with diagnosis and therapy of metabolic abnormalities and crystallization risks in patients with recurrent urolithiasis is presented. Since 1985, more than 900 persons with recurrent urolithiasis have been examined at the Metabolic Centre of the Hospital in Sternberk. The patients were examined routinely at ambulance or during hospitalization; the examination consisted of repeated urine and blood collections after the diet with various content of calcium and salt. All initial data (case history, physical finding, biochemistry, radiodiagnostics) were processed by a semi-expert computing program SOFT which was also used for monitoring...

[Thoracoscopic diagnosis of mediastinal lymphoma].

J Klein, V Král, C Neoral, E Faber

Vnitr Lek 1997, 43(12):787-789

The possibilities of invasive diagnostic procedures and their place in examination schedule are evaluated in a group of 36 patients. Authors point out the need of close inter-discipline cooperation. They highly appreciate accuracy and reliability of mediastinoscopy and videothoracoscopy, on the other side they show possible complications and contraindications of these procedures.

[Thallium perfusion scintigraphy and bicycle ergometry in the diagnosis of ischemic heart disease. Comparison with coronarography findings].

S Janousek, I Janda, P Simek, P Rotrekl, Z Horák

Vnitr Lek 1997, 43(12):790-794

In 76 patients (66 men and 10 women, age 20-71 years) with stable angina pectoris planar thallium myocardial perfusion scintigraphy, bicycle ergometry and coronary angiography were performed. Thallium scintigraphy was highly sensitive (97%) for detection of ischaemic heart disease, the sensitivity of ergometry was 75%. When comparing patients with affected 1, 2 and 3 coronary arteries perfusion scintigraphy had a sensitivity of 100%, 90% and 100% resp., while bicycle ergometry 62%, 90% and 82% resp. The specificity of perfusion scintigraphy was low (47%), compared with ergometry (60%). The finding of s reversible perfusion defect during scintigraphy...

[Magnetic resonance in cardiology--a new alternative in noninvasive diagnosis].

M Herman, E Sovová, J Bucil, J Lukl, D Marek

Vnitr Lek 1997, 43(12):795-800

The authors describe their initial experience with examination of the heart by magnetic resonance (MR) and discuss its position in the diagnostic algorithm of cardiac examinations:. They made 31 MR examinations of the heart in 30 patients. Echocardiography preceded 29 examinations. MR proved to be particularly useful where echocardiography did not lead to a decisive conclusion and called for confirmation by another method, or where it could not be carried out or its result was not consistent with the patient's clinical condition or the results of other examinations. The quality of the MR image was influenced most by the possibility of ECG gating. The...

[Ischemic heart disease and bilirubin levels in a group of hospitalized patients].

J Icsó, D Nanová

Vnitr Lek 1997, 43(12):801-803

During the last three years several papers were published, which found in large groups an inverse relationship between the bilirubin level and ischaemic heart disease. This relationship is typically U-shaped which means that with the rising bilirubin level the incidence of IHD declines but when the values are close to the upper normal range, the incidence of IHD rises again. This protective effect of bilirubin on the development of IHD is explained by the experimentally tested antioxidative action of bilirubin acting on LDL-cholesterol and thus inhibiting foam cell formation in the arterial wall. The authors decided to test this relationship in a group...

[Plasminogen activator inhibitor (PAI-1) and diabetes mellitus. I. Regulation of PAI-1 levels].

P Galajda, L Sutarík, L Vladár, J Stasko, P Kubisz, M Mokán

Vnitr Lek 1997, 43(12):804-808

Elevated PAI-1 levels were described in different insulin resistant conditions, incl. diabetes mellitus type II. In its formation probably several stimulating factors participate. Hitherto accomplished studies suggest not only the important effect of insulin acting synergically with very low density. lipoproteins (VLDL) on hepatocytes but also the importance of the endothelial pool where the action of proinsulin, VLDL and cytokines in synergy with Cai-dependent stimuli (oxidation stress, thrombin) is involved. Under certain circumstances also another adipocyte compartment may play a role, and a significant role of thrombocytes in raising the PAI-1...

[High-dose chemotherapy--a new hope for some patients with malignant tumors?].

J Mayer

Vnitr Lek 1997, 43(12):809-814

High-dosage chemotherapy is at present a very intensively investigated therapeutic procedure which rises great expectations. Administration of large doses of cytostatics is made possible by subsequent transplantation of autologous or allogenic haematopoietic progenitor cells (transplantation of peripheral stem cells or bone marrow). This reduces markedly the haematological toxicity of chemotherapy and it is possible to administer cytostatics in amounts at the non-haematological toxicity borderline. In the first part of the paper theoretical principles of high-dosage chemotherapy are analyzed, the relationship between the dosage of the drug and its...

[Prokinetic agents in the treatment of ulcer disease].

A Hep, J Dolina, J Prásek, P Dítě

Vnitr Lek 1997, 43(12):815-818