Vnitr Lek 2025, 71(2):E19-E24 | DOI: 10.36290/vnl.2025.025
Malnutrition in Whipple’s Disease: A Case Report
- Interní a kardiologická klinika, Fakultní nemocnice Ostrava
- Lékařská fakulta, Ostravská univerzita
Whipple‘s Disease (WD) is a rare multisystem disorder caused by the actinomycete Tropheryma whipplei, characterized by a diverse clinical presentation. The prodromal stage is often characterized by arthralgia, while the symptomatic stage predominantly manifests with gastrointestinal symptoms such as chronic diarrhea, abdominal pain, and weight loss. Duodenal biopsy remains the cornerstone of diagnosis, with PCR analysis providing a definitive confirmation. Treatment involves long-term antibiotic therapy. This case report describes a 65-year-old woman newly diagnosed with WD, presenting with severe malnutrition and notable rheumatological and hematological symptoms, outlining our therapeutic and nutritional interventions.
Keywords: arthralgia, malnutrition, Tropheryma whipplei, weight loss, Whipple’s disease
Accepted: March 18, 2025; Published: March 27, 2025 Show citation
