Vnitr Lek 2024, 70(5):276-283 | DOI: 10.36290/vnl.2024.056

Antibiotic therapy for the most common infections in outpatient practice

Milan Trojánek¹, Marek Štefan^{1, 2}, Ludmila Bezdíčková³, Michal Prokeš⁴, Helena Žemličková^{5, 6}

¹ Klinika infekčních nemocí a cestovní medicíny 2. LF UK a FN Motol, Praha

² Katedra infekčního lékařství, Institut postgraduálního vzdělávání ve zdravotnictví, Praha

³ Katedra všeobecného praktického lékařství, Institut postgraduálního vzdělávání ve zdravotnictví, Praha

⁴ DrugAgency, Praha

⁵ Ústav mikrobiologie 3. LF UK, Fakultní nemocnice Královské Vinohrady a SZÚ, Praha

⁶ Národní referenční laboratoř pro antibiotika, SZÚ, Praha

The World Health Organization (WHO) has identified antimicrobial resistance as one of the leading risks to global health. In 2019, antibiotic resistance led to 4.95 million deaths worldwide. The primary cause is the exposure of bacteria to antibiotics, especially in human medicine. There is evidence that improving antibiotic prescriptions can reduce antimicrobial resistance. Most antibiotics are prescribed to outpatients, often for respiratory infections, where they are frequently overused. To improve clinical practice, it is necessary to influence not only the quantity of prescribed antibiotics but also to prefer antibiotics with a lower potential for developing resistance and collateral damage. The aim of this article is to present the current guidelines of SKAP CLS JEP for the treatment of the most common infections in outpatient practice and to compare them with the guidelines of WHO, NICE, and other societies.

Keywords: antibiotics, antimicrobial resistance, bacteria, primary care, respiratory tract infections, skin and soft tissue infections, urinary tract infections.

Accepted: August 28, 2024; Published: September 4, 2024  Show citation