Vnitr Lek 2020, 66(5):275-281 | DOI: 10.36290/vnl.2020.082

Dyslipidemia in patients with chronic kidney disease: etiology and management

Magdaléna Dušejovská^1,2, Marek Vecka², Ivan Rychlík³, Aleš Žák²

¹ Dialyzační středisko Fresenius Medical Care Praha 10 - Královské Vinohrady

² IV. interní klinika 1. LF UK a VFN Praha

³ I. interní klinika 3. LF UK a FN Královské Vinohrady Praha

The worldwide population is burdened with chronic kidney disease (CKD) from 10-13 %. Patients with CKD subsequently die to cardiovascular disease (CVD) and their complications. In the Czech population, in 2016, the number of patients with end stage renal disease (ESRD) on regular dialytic treatment was 6 739, or 674/1 000 000 inhabitants. Overall mortality in regular dialysis treatment patients was 18.4 % in 2016, of which 43 % died of cardiovascular complications. In view of this fact, a number of expert groups are concerned, among other things, with the problems of lipid metabolism disorders, with the aim of finding a common predictive marker (preferably also therapeutically qualifiable) to stratify patients dialyzed or potentially indicating hypolipidemic therapy. The aim of possible interventions is to minimize cardiovascular risk and subsequent complications resulting from cardiovascular disease (CVD), thus improving the quality of life of regular dialysis treatment patients.

Keywords: dyslipidemia, hypolipidemic therapy, chronic kidney disease, regular dialysis treatment.

Published: August 1, 2020  Show citation