Vnitr Lek 2020, 66(4):259-266 | DOI: 10.36290/vnl.2020.071

Hyperuricemia in renal disease patients

Štěpán Bandúr
I. interní klinika 3. LF UK a FN Královské Vinohrady Praha

Hyperuricemia is a common laboratory finding in different types of patients. Except of those with acute or chronic gout, it is frequently found in patients with metabolic syndrome, patients with malignancies or renal impairment - acute kidney injury (AKI) and chronic kidney disease (CKD). Hyperuricemia might cause renal dysfunction or might be a part of laboratory abnormalities associated with loss of renal function as well. There is also large body of evidence of hyperuricemia as a potential cardiovascular (CV) risk factor, which might even more increase CV risk in CKD patients. Association of asymptomatic hyperuricemia and progression of CKD remaines controversial, as well as indication for hypouricemic treatment in this clinical setting.

Keywords: acute kidney injury (AKI), cardiovascular risk, hyperuricemia, chronic kidney disease (CKD), uric acid.

Published: June 1, 2020  Show citation

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Bandúr Š. Hyperuricemia in renal disease patients. Vnitr Lek. 2020;66(4):259-266. doi: 10.36290/vnl.2020.071.
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