Vnitr Lek 2015, 61(Suppl 5):50-55

Is iron important in heart failure?

Ján Murín*, Miroslav Pernický
I. interná klinika LF UK a UN Bratislava, Slovenská republika, prednostka doc. MUDr. Soňa Kiňová, CSc.

Iron deficiency is a frequent comorbidity in a patient with chronic heart failure, and it associates with a worse prognosis of that patient. Mainly worse quality of life and more rehospitalizations are in these iron deficient patients. Iron metabolism is rather complex and there is some new information concerning this complexity in heart failure. We distinquish an absolute and a functional iron deficiency in heart failure. It is this deficit which is important and not as much is anemia important here. Prevalence of anaemia in heart failure is about 30-50 %, higher it is in patients suffering more frequently heart failure decompensations. Treatment of iron deficiency is important and it improves prognosis of these patients. Most experiences there are with i.v. iron treatment (FERRIC HF, FAIR HF and CONFIRM HF studies), less so with per oral treatment. There are no clinical trials which analysed mortality influences.

Keywords: heart failure; iron metabolism in heart failure; prevalence of iron deficit; treatment of iron deficiency in heart failure

Received: June 23, 2015; Accepted: September 30, 2015; Published: October 1, 2015  Show citation

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Murín J, Pernický M. Is iron important in heart failure? Vnitr Lek. 2015;61(Supplementum 5):50-55.
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