Vnitr Lek 2012, 58(3):196-201

Vitamin D - remarks of known and overwiev of new facts

H. Matějovská Kubešová^1,*, J. Tůmová², V. Polcarová¹, H. Meluzínová¹

¹ Klinika interní, geriatrie a praktického lékařství Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednostka prof. MUDr. Hana Matějovská Kubešová, CSc.

² Oddělení klinické biochemie FN Brno, pracoviště Bohunice, přednosta doc. MUDr. Milan Dastych, CSc., MBA

Vitamin D as one of liposolubile vitamins was related to children age and skeleton at the clinical practice until now. There is lot of new information considering rather more complicated connection of vitamin D into many functions of human body during last years. On the other hand we are able to measure the serum level of vitamin D, so we recognized the possibility of long term significantly low levels of vitamin D in tenths percent of population. This review shows actual information about relationsship between vitamin D and organ systems and their disturbances. Long term low level of vitamin D potentiates cognitive deterioration in elderly, influences the mood up to depression appearance. The influence of vitamin D on immunity system and cancerogenesis appears to be of high importance too. From the senior's independence point of view the relationship between vitamin D and sarcopenia is very important especially in connection with osteoporosis prevention - the way how to reduce the danger of falls and osteoporotic fractures. Autoimmune diseases and diabetes mellitus are mentioned at the end of the review.

Keywords: vitamin D; bone; muscle; sarcopenia; cognitive functions; depression; cancer; autoimmunity; diabetes mellitus

Received: June 13, 2011; Accepted: October 4, 2011; Published: March 1, 2012  Show citation