Vnitr Lek 2011, 57(11):959-965

Pharmacotherapy of chronic heart failure after the first decade of 21st century

J. ©pinar1,*, J. Vítovec2, L. ©pinarová2
1 Interní kardiologická klinika Lékařské fakulty MU a FN Brno, pracoviątě Bohunice, přednosta prof. MUDr. Jindřich ©pinar, CSc., FESC
2 I. interní kardioangiologická klinika Lékařské fakulty MU a FN u sv. Anny Brno, přednosta prof. MUDr. Jiří Vítovec, CSc., FESC

We provide an overview of the main principles of pharmacological treatment of chronic heart failure. Chronic heart failure is considered to be an epidemic of the 21st century; in the Czech Republic, around 200,000 persons suffer from this condition. Over the last decade, pharmacological and non-pharmacological treatment of heart failure has undergone significant progress and new knowledge arises every year. Generally accepted pharmacological treatment steps include administration of ACE inhibitors, AII antagonists (ARB) or beta-blockers, discussions exists on an indication for digoxin, diuretics and lipid-lowering drugs as well as on the importance of ACE-I and ARB. The role of antiarrhythmics is unclear and 2009-2011 have brought about some completely new drug groups - If channel blockers, factor Xa blockers, thrombin blockers and other agents.

Keywords: heart failure; ACE inhibitors; beta-blockers; digoxin; ivabradin

Received: September 6, 2011; Published: November 1, 2011  Show citation

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©pinar J, Vítovec J, ©pinarová L. Pharmacotherapy of chronic heart failure after the first decade of 21st century. Vnitr Lek. 2011;57(11):959-965.
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