Vnitr Lek 2011, 57(2):163-169

Alcoholic cardiomyopathy - still a topical diagnosis

P. Kyčina1,*, J. Murín2
1 Interné oddelenie - Jednotka intenzívnej starostlivosti Liptovskej nemocnice Liptovský Mikuláš, Slovenská republika, prednosta prim. MUDr. Viliam Iľanovský
2 I. interná klinika Lekárskej fakulty UK a FNsP Bratislava, Slovenská republika, prednostka doc. MUDr. Soňa Kiňová, PhD.

Even though extensive experimental as well as clinical evidence exists for adverse cardiac effects of alcohol, pathogenesis and incidence of alcoholic cardiomyopathy is not fully understood. From the genetic level and understanding of the pathogenesis of the toxic effects of alcohol on the heart we come to discuss the diagnosis and treatment of the disease that, in the context of co-morbidities and complications (hypertension, diabetes, arrhythmias, heart failure), continues to represent an significant clinical entity with an important impact on patient prognosis.

Keywords: alcohol; alcoholic cardiomyopathy; complications; prognosis

Received: June 6, 2010; Accepted: October 30, 2010; Published: February 1, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Kyčina P, Murín J. Alcoholic cardiomyopathy - still a topical diagnosis. Vnitr Lek. 2011;57(2):163-169.
Download citation

References

  1. Widimský J, Víšek V. Preventivní kardiologie. Praha: Avicenum 1981: 213-217.
  2. Piano MR. Alcoholic cardiomyopathy: incidence, clinical characteristics and pathophysiology. Chest 2002; 121: 1638-1650. Go to original source... Go to PubMed...
  3. Maron BJ, Towbin JA, Thiene G et al. Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 2006; 113: 1807-1816. Go to original source... Go to PubMed...
  4. Remme WJ, Swedberg K. Task Force for the Diagnosis and Treatment of Chronic Heart Failure, European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J 2001; 22: 1527-1560. Go to original source... Go to PubMed...
  5. Piano MR. Alcohol and heart failure. J Card Fail 2002; 8: 239-244. Go to original source... Go to PubMed...
  6. Fauchier L, Babuty D, Poret P et al. Comparison of long-term outcome of alcoholic and idiopathic dilated cardiomyopathy. Eur Heart J 2000; 21: 306-314. Go to original source... Go to PubMed...
  7. Nicolás JM, Fernández-Solà J, Estruch R et al. The effect of controlled drinking in alcoholic cardiomyopathy. Ann Intern Med 2002; 136: 192-200. Go to original source... Go to PubMed...
  8. Rusnák I, Žuffa M, Pullmann R et al. Validita laboratórnych vyšetrení pre diagnostiku alkoholizmu a alkoholických poškodení pečene. Vnitř Lék 1991; 37: 578-584. Go to PubMed...
  9. Gvozdjáková A. Metabolické zmeny v myokarde po podávaní etanolu. Rigorózna práca. Bratislava 1972.
  10. Kyčina P. Alkoholová kardiomyopatia - stanovenie vybraných funkčných a morfologických parametrov srdca echokardiograficky vzhľadom ku kvantite, kvalite a dobe konzumu alkoholu. Cardiology 2008; 17 (Suppl 2): 19S-20S.
  11. Moushmoush B, Abi-Mansour P. Alcohol and the heart. Arch Intern Med 1991; 151: 36-40. Go to original source...
  12. Nicolas S, Aberle I. Experimental assesment of the role of Acetaldehyde in Alcoholic Cardiomyopathy. Available from: http://www.biologicalprocedures.com/bpo/arts/1/412004.
  13. Gregor P, Widimský P. Kardiologie v praxi. Praha: Galén 1999.
  14. Niederle P. Echokardiografie dospělých. Praha: Triton 2002.
  15. Silvestry FE, Popjes E. Alcoholic Cardiomyopathy. Emedicine J 2002; 3. Available from: http://www.emedicine.com/med/topic286.htm.
  16. Farský Š, Lepej J, Bakos K. Nukleárna kardiológia. Martin: Osveta 1989.
  17. Zima T, Mareček Z, Špičák J et al. Poškození jater, pankreasu a trávicího ústrojí alkoholem. Praha: Medprint 1996: 7-14.
  18. Gvozdják J, Gvozdjáková A, Kucharská J et al. Novšie poznatky o kardiomyopatiách. Bratisl Lek Listy 1994; 95: 389-390. Go to PubMed...
  19. Ehrman J. Alkohol a játra. Lék Listy 2003; 48: 11. Go to original source...
  20. Kolbel F. Charakteristika a výskyt kardiomyopatií. Novinky v medicíně. Praha: Avicenum 1981.
  21. Riečanský I. Srdcové zlyhanie. Bratislava: Herba 1998.
  22. Fernández-Solà J, Nicolás JM, Oriola J et al. Angiotensin-converting enzyme gene polymorphism is associated with vulnerability to alcoholic cardiomyopathy. Ann Intern Med 2002; 137: 321-326. Go to original source... Go to PubMed...
  23. Duan J, McFadden GE, Borgerding AJ et al. Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes. Am J Physiol Heart Circ Physiol 2002; 282: H1216-H1222. Go to original source... Go to PubMed...
  24. Fernández-Solà J, Nicolás JM, Oriola J et al. Angiotensin-converting enzyme gene polymorphism is associated with vulnerability to alcoholic cardiomyopathy. Ann Intern Med 2002; 137: 321-326. Go to original source... Go to PubMed...
  25. Richardson P, McKenna W, Bristow M et al. Report of the 1995 WHO/ISH task force on the definition and classification of cardiomyopaties. Circulation 1996; 93: 841-842. Go to original source... Go to PubMed...
  26. National Institute on Alcohol Abuse and Alcoholism. Alcohol and cardiovascular system. Available from: http://www.niaaa.nih.gov/extramural/acs.htm.
  27. Wakabayashi I, Kobaba-Wakabayashi R, Masuda H. Relation of drinking alcohol to atherosclerosis risk in type 2 diabetes. Diabetes Care 2002; 25: 1223-1228. Go to original source... Go to PubMed...
  28. Ďuriš I, Hulín I, Bernadič M. Princípy internej medicíny. Bratislava: Slovak Academic Press 2001.
  29. Gregor P, Widimský P. Kardiologie. Praha: Galén 1999.
  30. Donohue TM Jr. The ubiquitin-proteasome system and is role in ethanol-induced disorders. Addict Biol 2002; 7: 15-28. Go to original source... Go to PubMed...
  31. Guertl B, Noehammer C, Hoefler G. Metabolic cardiomyopathies. Int J Exp Pathol 2000; 81: 349-372. Go to original source... Go to PubMed...
  32. Lee WK, Regan TJ. Alcoholic cardiomyopathy: is it dose-dependent? Congest Heart Fail 2002; 8: 303-306. Go to original source... Go to PubMed...
  33. Dettmeyer R, Reith K, Madea B. Alcoholic cardiomyopathy versus chronic myocarditis - immunohistological investigations with LCA, CD3, CD68 and tenascin. Forensic Sci Int 2002; 126: 57-62. Go to original source... Go to PubMed...
  34. Lazarini L, Ghio S. Echocardiographic evolution of left ventricular and left atrial thrombi in a patient with left ventricular dysfunction due to alcoholic cardiomyopathy, chronic atrial fibrillation and multiple non-fatal systemic embolisms. Acta Cardiol 2001; 56: 131-135. Go to original source... Go to PubMed...
  35. Schoppet M, Maisch B. Alcohol and the heart. Herz 2001; 26: 345-352. Go to original source... Go to PubMed...
  36. Fernández-Solà J, Estruch R, Nicolás JM et al. Comparison of alcoholic cardiomyopathy in women versus men. Am J Cardiol 1997; 80: 481-485. Go to original source... Go to PubMed...
  37. Klatsky AL. Moderate drinking and reduced risk of heart disease. Alcohol Res Health 1999; 23: 15-23.
  38. Ajani UA, Gazino JM, Lotufo PA et al. Alcohol consumption and risk of coronary heart disease by diabetes status. Circulation 2000; 102: 500-505. Go to original source... Go to PubMed...
  39. Solomon CG, Hu FB, Stampfer MJ et al. Moderate alcohol consumption and risk of coronary heart disease among women with type 2 diabetes mellitus. Circulation 2000; 102: 494-499. Go to original source... Go to PubMed...
  40. Novotný V, Heretik A, Heretik A ml. et al. Epidemiológia alkoholizmu vo svete a na Slovensku. Lek Obzor 2010; 41: 103.
  41. Hlásenský V. Magické myšlení: jsem lékař, ne pacient. Zdravotnické noviny 2003; 48: 17.
  42. Johnson K. Moderate drinking may help acute MI survival. Fam Pract News 2000. Available from: http://www.findarticles.com.
  43. Gavazzi A, De Maria R, Parolini M et al. Alcohol abuse and dilated cardiomyopathy in men. Am J Cardiol 2000; 85: 1114-1118. Go to original source... Go to PubMed...
  44. Šamánek M. Každodenní pití malého množství alkoholu je zdraví prospěšné. Cor Vasa 2004; 46: 97-99.
  45. Braunwald E. Heart Disease. 6th ed. Philadelphia, Toronto, London: W.B. Saunders Company 2001.
  46. Klabník A, Murín J, Kyčina P. Do we need new quality markers for chronic heart failure? Bratisl Lek Listy 2010; 111: 392-397. Go to PubMed...
  47. Ehrmann J, Schneiderka P, Ehrmann J. Alkohol a játra. Praha: Grada Publishing 2006: 138-139.
  48. Kupari M. Reversibility of alcoholic cardiomyopathy. Postgrad Med J 1984; 60: 151-154. Go to original source... Go to PubMed...
  49. Corović N, Duraković Z, Misigoj-Duraković M. Dispersion of the corrected QT and JT interval in the electrocardiogram of alcoholic patients. Alcohol Clin Exp Res 2006; 30: 150-154. Go to original source... Go to PubMed...
  50. Lang CH, Frost RA, Summer AD et al. Molecular mechanisms responsible for alcohol-induced myopathy in skeletal muscle and heart. Int J Biochem Cell Biol 2005; 37: 2180-2195. Go to original source... Go to PubMed...
  51. Morton A. Pregnancy outcome in a mother with alcoholic cardiomyopathy. Aust N Z J Obstet Gynaecol 2005; 45: 328-330. Go to original source... Go to PubMed...
  52. Li Q, Ren J. Cardiac overexpression of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: role of Akt, mammalian target of rapamycin and ribosomal p70s6 kinase. Alcohol Alcohol 2006; 41: 585-592. Go to original source... Go to PubMed...
  53. Oba T, Maeno Y, Ishida K. Differential contribution of clinical amounts of acetaldehyde to skeletal and cardiac muscle dysfunction in alcoholic myopathy. Curr Pharm Des 2005; 11: 791-800. Go to original source... Go to PubMed...
  54. Djoussé L, Gaziano JM. Alcohol consumption and heart failure in hypertensive US male physicians. Am J Cardiol 2008; 102: 593-597. Go to original source... Go to PubMed...
  55. Poloncová E. Prehľady a štatistiky za okres Liptovský Mikuláš. Štátny zdravotný ústav Liptovský Mikuláš 2003.
  56. Møller S, Henriksen JH. Cardiovascular complications of cirrhosis. Postgrad Med J 2009; 85: 44-54.
  57. Trejbal K, Mitro P. ECG changes in alcoholic intoxication. Vnitř Lék 2008; 54: 410-414. Go to PubMed...
  58. Djoussé L, Gaziano M. Alcohol consumption and heart failure: a systematic review. Curr Atheroscler Rep 2008; 10: 117-120. Go to original source... Go to PubMed...
  59. Costanzo S, Di Castelnuovo A, Donati MB et al. Cardiovascular and overall mortality risk in relation to alcohol consumption in patients with cardiovascular disease. Circulation 2010; 121: 1951-1959. Go to original source... Go to PubMed...
  60. Klatsky AL. Alcohol and cardiovascular mortality: common sense and scientific truth. J Am Coll Cardiol 2010; 55: 1336-1338. Go to original source... Go to PubMed...
  61. Mukamal KJ, Chen CM, Rao SR et al. Alcohol consumption and cardiovascular mortality among U.S. adults, 1987 to 2002. J Am Coll Cardiol 2010; 55: 1328-1335. Go to original source... Go to PubMed...
  62. Zardi E, Abbate A, Dobrina A et al. Cirrhotic cardiomyopathy. J Am Coll Cardiol 2010; 56: 539-549. Go to original source... Go to PubMed...
  63. Jensen M, Mukamal K, Overvad K et al. Alcohol consumption, TaqIB polymorphism of cholesteryl ester transfer protein, high-density lipoprotein cholesterol, and risk of coronary heart disease in men and women. Eur Heart J 2008; 29: 104-112. Go to original source... Go to PubMed...
  64. Janszky I, Ljung R, Ahnve S et al. Alcohol and long-term prognosis after a first acute myocardial infarction: the SHEEP study. Eur Heart J 2008; 29: 45-53. Go to original source... Go to PubMed...
  65. Vavrušová L. Miesto silymarínu v liečbe alkoholového poškodenia pečene. Súč Klin Prax 2009; 2: 21-24.
  66. Trejbal K. Alkohol a poruchy srdcového rytmu. Intern Med 2010; 10: 432-436.
  67. Feszterová M, Kašiarová S. Influence of climate conditions and air contaminations on village inhabitants health. 4th Meeting on chemistry and life. Chemické listy 2008; 102: 300-302.
  68. O'Keefe JH, Bybee KA, Lavie CJ. Alcohol and cardiovascular health: the razor-sharp double-edged sword. J Am Coll Cardiol 2007; 50: 1009-1014. Go to original source... Go to PubMed...




Vnitřní lékařství

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.