Vnitr Lek 2011, 57(2):132-134
Is there a genetic determination of the age of type 2 diabetes mellitus diagnosis? Revised concept of the "thrifty genotype" - editorial
- Ústav patologické fyziologie Lékařské fakulty MU Brno, přednostka prof. MUDr. Anna Vašků, CSc.
Received: January 24, 2011; Published: February 1, 2011 Show citation
References
- Florez JC, Hirschhorn J, Altshuler D. The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits. Annu Rev Genomics Hum Genet 2003; 4: 257-291.
Go to original source...
Go to PubMed...
- Gloyn AL. The search for type 2 diabetes genes. Ageing Res Rev 2003; 2: 111-127.
Go to original source...
Go to PubMed...
- Voight BF, Scott LJ, Steinthorsdottir V et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet; 2008; 42: 579-589.
Go to original source...
Go to PubMed...
- Staiger H, Machicao F, Fritsche A et al. Pathomechanisms of type 2 diabetes genes. Endocr Rev 2009; 30: 557-585.
Go to original source...
Go to PubMed...
- Zeggini E, McCarthy MI. TCF7L2: the biggest story in diabetes genetics since HLA? Diabetologia 2007; 50: 1-4.
Go to original source...
Go to PubMed...
- McCarthy MI, Zeggini E. Genome-wide association studies in type 2 diabetes. Curr Diab Rep 2009; 9: 164-171.
Go to original source...
Go to PubMed...
- Durbin RM, Abecasis GR, Altshuler DL et al. A map of human genome variation from population-scale sequencing. Nature 2009; 467: 1061-1073.
Go to original source...
- Ruchat SM, Elks CE, Loos RJ et al. Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies. Acta Diabetol 2009; 46: 217-226.
Go to original source...
Go to PubMed...
- Cauchi S, Meyre D, Dina C et al. Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes 2006; 55: 2903-2908.
Go to original source...
Go to PubMed...
- Lehman DM, Hunt KJ, Leach RJ et al. Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans. Diabetes 2007; 56: 389-393.
Go to original source...
Go to PubMed...
- Kimber CH, Doney AS, Pearson ER et al. TCF7L2 in the Go-DARTS study: evidence for a gene dose effect on both diabetes susceptibility and control of glucose levels. Diabetologia 2007; 50: 1186-1191.
Go to original source...
Go to PubMed...