Vnitr Lek 2008, 54(6):632-637

Preparation of patients with haemostatic disorder for invasive medical interventions

M. Penka^1,*, A. Buliková¹, P. Smejkal¹, J. Kissová¹, M. Matýšková¹, J. Gumulec², S. Králová², M. Šlechtová¹, G. Chlupová¹

¹ Univerzitní centrum pro trombózu a hemostázu MU Brno a Oddělení klinické hematologie FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Miroslav Penka, CSc.

² Onkologické centrum J. G. Mendla Nový Jičín, přednosta prim. MUDr. Jaromír Gumulec

The current trend in medicine is to sustain the possibility for necessary procedures to be performed in patients who suffer from haemostatic disorders which complicate eventual surgery. Among such disorders are congenital blood coagulation disorders, haemostatic disorders concomitant with other diseases and also therapies which affect haemostasis either on purpose or as part of adverse effects. Among coagulation disorders are congenital haemorrhagic or thrombotic conditions, acquired blood coagulation disorders - combined in the vast majority of cases - and associated with pregnancy, severe internal diseases and surgery related diseases, severe injuries, wounds, burns, malignancies, systemic connective tissue diseases, inflammatory bowel disease, and a number of other diseases. A separate issue is that of anticoagulation therapy - both antiplatelet, used in the treatment or prevention of venous thrombosis, and anticoagulation, predominantly used to manage venous thromboembolism. Also considered should be any therapy which may have a negative impact on coagulation due to its adverse effects.

Keywords: surgery; haemorrhage; thrombosis; transfusion preparations; blood derivatives; heparin; warfarin

Received: February 4, 2008; Published: June 1, 2008  Show citation