Vnitr Lek 2008, 54(2):146-149

Definition of 24hour ambulatory blood pressure values corresponding to office blood pressure values of 130/80 mm Hg

I. Řiháček^1,*, M. Souček¹, P. Fráňa¹, M. Plachý¹, A. Vašků², V. Znojil²

¹ II. interní klinika Lékařské fakulty MU a FN u sv. Anny Brno, přednosta doc. MUDr. Miroslav Souček, CSc.

² Ústav patologické fyziologie Lékařské fakulty MU Brno, přednostka prof. MUDr. Anna Vašků, CSc.

Background:
Ambulatory blood pressure monitoring (ABPM) provides a profile of blood pressure (BP) away from the medical environment and has been shown to be a stronger predictor of cardiovascular morbidity and mortality than office BP measurement. There are known the normal BP values for ABPM in general population with office BP value 140/90 mm Hg, but don't are known normal values for ABPM of patients with high risk hypertension which needs to have office BP below 130/80 mm Hg. Aim of study: Definition of normal BP value of ABPM in patients with office BP130 and/or 80 mm Hg.

Methods:
BP measurement in 241 healthy subjects by ABPM and mercury sphygmomanometer according to European Hypertension Society criteria. Subject selection with following criteria: mean office systolic blood pressure 128-132 mm Hg or diastolic blood pressure 78-82 mm Hg. Exclusion ABPM curves with white-coat hypertension and masked hypertension. All office and ABPM inclusion criteria fulfill 37 subjects for systolic blood pressure, mean age 44 years and 48 subjects for diastolic blood pressure, mean age 45 years.

Results:
Mean office systolic BP 129.9 ± 1.6 mm Hg, diastolic BP 80.2 ± 1.5 mm Hg. Mean 24hour systolic BP 119.1 ± 12.3 (95% CI, 119.0-119.3) mm Hg, diastolic BP 71.4 ± 10.2 (95% CI, 71.3-71.5) mm Hg, day time systolic BP 123.7 ± 9.0 (95% CI, 123.6-123.8) mm Hg, diastolic BP 75.4 ± 7.0 (95% CI, 75.3-75.5) mm Hg, night time systolic BP 105.8 ± 10.4 (95% CI, 105.7-105.9) mm Hg and diastolic BP 59.8 ± 9.0 (95% CI, 59.7-59.8) mm Hg.

Conclusion:
The normal BP value of ABPM in patients with office BP 130/80 mm Hg is for 24hour BP 119/71 mm Hg, day time BP 124/75 mm Hg and night time BP 106/60 mm Hg.

Keywords: 24hour ambulatory blood pressure monitoring; high risk hypertension; normal values

Received: October 12, 2007; Accepted: November 9, 2007; Published: February 1, 2008  Show citation