Vnitr Lek 1996, 42(1):37-42

[Use of beta-blockers in the treatment of chronic heart failure].

J Sutka, S Cagán: IV. interná klinika LF UK, Bratislava.

Recently in the world literature with increasing frequency reports are found on clinical studies investigating the use of beta-blockers in the treatment of chronic heart failure. The authors present a review of the problem comprising pathophysiological mechanisms at a receptor level up to investigations of the effect of beta-blockers on haemodynamics, the functional state of the left ventricle and survival. Although this promising and frequently controversial treatment is not accepted universally so far, partial data in the mentioned investigations indicate that when a more accurate dosage pattern is established and indications are specified in more detail, the use of beta-blockers is one way how to approach - in addition to the use of diuretics, cardiotonics and angiotensin converting enzyme inhibitors - a comprehensive therapeutic control of chronic heart failure.