Vnitr Lek 1995, 41(4):252-257

[Postischemic ("stunned") and chronic ischemic ("hibernating") cardiac muscle].

M Takác, S Koval, V Takác
Geriatrické centrum sv. Lukása.

Stunning of the heart muscle is a postischaemic dysfunction observed after reperfusion. The stunned heart muscle is functional, the restoration of contractility is slow. The stunning of the heart muscle is probably due to a partial disorder of the electromechanical mechanisms caused by impaired calcium homeostasis. Substances which protect against the development of stunning are substances which eliminate oxygen radicals and calcium channel blockers which adjust the calcium homeostasis in cells. The "hibernating myocardium" is a state of contractile dysfunction during chronic hypoperfusion of the heart muscle. When the blood flow is restored, the contractility improves gradually. The second generation of calcium antagonists is effective in hibernated heart muscles due to their selective coronary artery dilating effect.

Keywords: Animals; Humans; Myocardial Contraction; Myocardial Ischemia, physiopathology, ; Myocardial Stunning, physiopathology,

Published: April 1, 1995  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Takác M, Koval S, Takác V. [Postischemic ("stunned") and chronic ischemic ("hibernating") cardiac muscle]. Vnitr Lek. 1995;41(4):252-257.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)

    • Return to the content


    Vnitřní lékařství

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.