Vnitr Lek 1995, 41(4):243-247

[Tolerance and results of treatment of Hodgkin's disease].

M Krahulová, M Pisarcíková, Z Adam, J Vorlícek, N Hejlová, J Mayer, S Spelda

II. interní klinika FNsP, Brno-Bohunice.

At present the accepted standard chemotherapeutic treatment of Hodgkin's disease is therapy according to the MOPP pattern (mustargen, vincristine, procarbazine and prednisone) alternating with the ABVD therapeutic pattern (adriamycin, bleomycin, vinblastine and dacarbazine). It is substantial for achieving optimal results to administer the planned treatment in non-reduced doses and at the scheduled time. In the submitted paper the authors describe the tolerance of chemotherapy and its results in 15 patients and the tolerance of radiotherapy in another four patients suffering from Hodgkin's disease. Complications of chemotherapy (leukopenia and infection) caused an overall average retardation of chemotherapy of 37 days per patient. This interval would be certainly longer if the patients were not given Leucomax Schering Plough. From a total of four patients given radiotherapy Leucomax had to be administered to two, otherwise radiotherapy would have had to be discontinued on account of a decline of leucocytes.

Keywords: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols, adverse effects, ; Female; Hodgkin Disease, therapy, ; Humans; Male; Middle Aged; Radiotherapy, adverse effects,

Published: April 1, 1995  Show citation