Vnitr Lek 1994, 40(12):773-775
[Resistance to activated protein C, so-called APC resistance: the first two cases in Slovakia].
- Klinika hematológie a transfuziológie MFN Martin.
For the anticoagulant action of activated protein C (APC) in addition to protein S another newly detected cofactor is essential. Its deficiency is described as APC-resistance. This defect which is closely associated with the molecule of the factor V seems to be the most frequent cause of thrombophilia. The authors describe two patients where APC-resistance was diagnosed for the first time in Slovakia.
Keywords: Adult; Female; Humans; Protein C Deficiency; Thrombosis, blood,
Published: December 1, 1994 Show citation