Vnitr Lek 1991, 37(4):366-368

[Plasma iron levels in patients with rheumatoid arthritis].

M Kucera, H Brabcová: I. interní klinika KUNZ FN Plzen.

In 50 patients with confirmed or classical rheumatoid arthritis the serum iron level (FeS) was examined (in some repeatedly), the total number of examinations being 82. In 51.1% reduced values were recorded. In 27 subjects of the group the total iron binding capacity was assessed. In none of the patients reduced values were found, in 24 the values were at the upper borderline of normal values and in one instance the value was elevated. In 13 patients with a low FeS with a normal or elevated total iron binding capacity Ferronat Retard was administered. The FeS level reached relatively rapidly normal values which in the author's opinion is rather a manifestation of receding activity of rheumatoid arthritis. They consider administration of iron preparations even in patients with a relatively high total iron binding capacity problematical, except when there is justified suspicion of iron ion losses via the gastrointestinal tract or in malnutrition. Iron administration did not cause deterioration of the rheumatic process.