Vnitr Lek 2017, 63(7-8):531-534 | DOI: 10.36290/vnl.2017.108
Viral hepatitis C and organ transplantation
- Centrum kardiovaskulární a transplantační chirurgie, Brno
At the Centre for Cardiovascular and Transplantation Surgery, Brno (CKTCH), a total of 638 liver transplantations were performed from the beginning of the transplantation programme on 2/2 1983 to 1/1 2017. Of the overall number of 638 transplantations indicated based on cirrhosis with chronic hepatitis C (HCV), 68 patients (11 %) underwent liver transplantation. Patients with HCV diagnosis were treated both while on the waiting list and after liver transplantation (LT). There was interferon as well as interferon-free therapy used during the treatment. 15 patients received interferon therapy after LT with only 2 of them achieving a sustained virological response 2/15 (13 %). 28 patients received interferon-free therapy after LT. A sustained virological response (SVR 12) was reached by 26/28 (93 %) patients.
Keywords: liver transplantation; viral hepatitis C
Received: May 29, 2017; Accepted: June 20, 2017; Published: July 1, 2017 Show citation
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