[Adefovir dipivoxil--a further step in the control of chronic viral hepatitis B. There is still a long way to go].

P Husa

Vnitr Lek 2004, 50(3):177-180

[Iron, free radicals and atherosclerosis].

J Racek

Vnitr Lek 2004, 50(3):181-183

[Is there a relation between serum ferritin levels, oxidized LDL antibodies and vitamins and risk for coronary atherosclerosis].

V Soska

Vnitr Lek 2004, 50(3):183-185

[Percutaneous revascularization and elevation of troponin].

J Bělohlávek

Vnitr Lek 2004, 50(3):185-187

[Recommendations for diagnosis and therapy of chronic heart failure 2001-2003].

J Spinar, L Spinarová

Vnitr Lek 2004, 50(3):187-196

[Ferritin, oxidative stress and coronary atherosclerosis].

P Kraml, J Potocková, H Koprivová, S Stípek, J Crkovská, T Zima, M Anděl

Vnitr Lek 2004, 50(3):197-202

BACKGROUND AND AIM: In the recent years several studies showed the association between body iron stores, represented by serum ferritin, and atherosclerosis. It was proposed that iron bound to ferritin catalyzes the formation of highly reactive forms of oxygen free radicals which subsequently cause the oxidative modification of atherogenic lipoproteins. Aim of our study was to compare serum ferritin concentrations and certain markers of oxidative stress in patients with and without coronarographically assessed coronary vascular disease.METHODS AND RESULTS: Measurements were performed in 216 subjects at the age of 35-60 years. The patient group...

[Increase in troponin levels after coronary angioplasty (PTCA) in stable angina pectoris].

I Varvarovský, M Brtko, M Branny

Vnitr Lek 2004, 50(3):203-207

GOAL: To determine frequency of elevated troponin levels following PTCA in patients with stable angina pectoris. To identify risk factors related to troponin elevation.METHOD: Multicentric prospective study. Troponin I level (cTnI) was determined in a group of 261 patients treated for stable angina pectoris with coronary angioplasty (PTCA) 12 hours after the intervention. A group of patients with cTnI levels above the upper level of a normal range was compared to patients without troponin elevation. Clinical, angiography, and peri-procedural indicators were assessed and frequency of their incidence in both groups of patients was compared.RESULTS:...

[Can serologic markers be indicators of dietary errors in patients with celiac disease?].

A Ilavská, I Beno, P Gomolcák, E Paulovicová

Vnitr Lek 2004, 50(3):208-212

Coeliac disease is a disease of small intestine requiring life-long strict gluten free diet to avoid acute and chronic complications. To reach maximum adherence to the diet is in some of coeliac patients, especially adults, difficult because it requires distinct changes in eating habits. To diagnose coeliac disease tests of antigliadin and anti-endomysial antibodies in serum are used. Authors monitored levels of antibodies in 32 adults 3, 6, and 12 month after histology validation of coeliac disease and after recommendation of a gluten free diet. The results were compared with data from nutritional history. Maximum adherence to the diet indicated 24...

[Causes of hospitalization in patients on chronic hemodialysis].

M Funiaková, S Funiaková, A Jezíková, B Holman, M Mokán, S Funiak

Vnitr Lek 2004, 50(3):213-217

UNLABELLED: Patients taking dialysis regularly form a group with higher morbidity and mortality compared with common population. The risk factors of the hospitalization in future in these patients are supposed to be: older age, history of cardiovascular disease, comorbidity, vascular access other than arterio-venous fistula, certain types of nephropathy and serum albumin level < 30 g/l. The number of patients in chronic dialysis treatment in Slovakia rises. Therefore we have performed a retrospective study. It's aim was to evaluate the main reasons and risk factors of hospitalizations in chronic haemodialysis patients in Turciansky region.METHODS:...

[Treatment of chronic postirradiation proctitis with argon plasma coagulation ].

O Urban, J Chalupa, P Vítek, P Reha

Vnitr Lek 2004, 50(3):218-221

Chronic radiation proctitis calls for a disease of the rectum due to irradiation of pelvic malignancies. The results of treatment of 8 patients with hematochezia from chronic radiation proctitis are presented here. They were treated with argon plazmakoagulation during 1-4 sessions. Hematochezia has disappeared in all cases. Rectal pain was the reason for hospitalization in one case. After the treatment, improved quality of live was claimed by all patients.

[Adefovir dipivoxil is a new drug for treatment of chronic hepatitis B].

J Stránský

Vnitr Lek 2004, 50(3):222-224

Adefovir dipivoxil is a new nucleotide analog derived from adenosin-monophosphate. At the 10 mg/day dose significantly decreases HBV DNA in serum, activity of transaminases, and leads to better histology results in liver assessment of adults with hepatitis B in the phase of active viral replication. Treatment with Adefovir dipivoxil is a long term treatment (48 weeks), it is well tolerated, and side effects are moderate and reversible. It can be administered to HBeAg positive patients, to patients with HBV mutant unable to create HBeAg if positive HBV DNA in serum, and to patients with lamivudine resistant HBV mutant.

[Diagnosis and therapy of chronic heart failure. European Cardiology Society Commission for Preparation of Practical Recommendations and the Conference on Improving the Quality of Clinical Practice and Patient Care in Europe].

Vnitr Lek 2004, 50(3):225-232

[Recommendations for diagnosis and therapy of chronic heart failure 2001--the short version].

J Spinar, J Hradec, I Málek, J Toman

Vnitr Lek 2004, 50(3):233-239

[Acute aortic dissection in a female patient with Marfan syndrome].

P Koleckár

Vnitr Lek 2004, 50(3):240-243

The group of patients with the Marfan syndrome is used to suffer from aneurysm and dilatation of the ascendent aorta, therefore the reason echocardiography examination is necessary. But in spite of this, although the dimensions (measures) are stable, we do really not know when the dissection appeared. This complication is the most usual cause of death these patients. But if we recognize the diagnosis in time and if we treat it correctly, this complication can be treated with the great difference in mortality. That is while we must think of this possible complication in case of atypical breast ache. The following case describes the acute dissection...

[Large-droplet liver steatosis in celiac disease].

L Husová, M Senkyrík, J Lata, D Stratil, P Hrobar, P Husa, J Utěsený

Vnitr Lek 2004, 50(3):244-248

Authors monitored a case of a 25 years old woman who was admitted for swelling of lower limbs. Laboratory results showed hypoproteinemia, elevation of liver enzymes, and prolonged prothrombin time. Ultrasound examination proved hepatomegalia with diffusely hyperechogenic liver without central lesion. Computer tomography confirmed hepatomegalia with diffusely hyperechogenic liver and a suspicion of liver steatosis was expressed. Liver biopsy confirmed serious diffuse large droplet steatosis of unclear genesis. Carried out examinations excluded infectious and autoimmune liver diseases, metabolic diseases, and congenital liver diseases (Wilson's disease,...