[Rights of terminally ill and dying persons to self determination (on a document from a parliamentary meeting of the European Council].

M Munzarová

Vnitr Lek 2001, 47(3):131-133

[Detection programme for diabetes mellitus type 2 in the Czech Republic--initial results].

J Perusicová

Vnitr Lek 2001, 47(3):134-139

Detection programmes and screening activities with the objective to reveal risk groups with asymptomatic diabetes mellitus or impaired glucose tolerance are an important tool for reducing the morbidity and mortality of type 2 diabetics from cardiovascular diseases. The detection programme in the Czech Republic was focused on the risk group of the population above 45 years of age. During the screening in which 120 general practitioners and 20 diabetolgists participated a total of 30672 subjects were examined and the results were evaluated statistically in 26577 subjects (86.52%). Diabetes mellitus was detected in 2.43% of the examined subjects and impaired...

[The prevalence of undiagnosed type 2 diabetes mellitus in consulting rooms of general practitioners].

J Vozár,

Vnitr Lek 2001, 47(3):140-145

UNLABELLED: The aim of study was to estimate the prevalence of newly detected type 2 diabetic patients and compare it with prevalence of registered type 2 diabetic patients in the Slovak republic. The second aim was to improve the cooperation between general practitioners and diabetologists in the detection of unrecognized diabetes.PATIENTS AND METHODS: Seventy-six general practitioners were involved in Slovak Diabetologic Detection Program. Randomly taken capillary glucose (glucometer One-Touch, Lifescan) was measured in 18,942 probands over 40 years of age with one or more risk factors for type 2 diabetes in nine regions of Slovakia during a...

[Prevalence of dyslipidaemia, hypertension and vascular complications in newly diagnosed diabetics (prospective study: part 2)].

J Perusicová

Vnitr Lek 2001, 47(3):146-150

UNLABELLED: In a 10-year prospective study of a group of 314 newly manifested diabetics (1988-1991) aged 20-65 years the authors follow up the development of diabetic complications and therapeutic methods used in diabetes. 85 patients were classified on detection of diabetes as diabetes mellitus (DM) type 1, 228 as DM type 2. At the age under 30 years there were 10 subjects (group M), the remainder (304) formed group A. In this second part of the initial results the authors provide information on biochemical changes, prevalence of hypertension and vascular complications already during manifestation of DM. Hypercholesterolaemia was detected in 29% of...

[Mummified Hodgkin and Reed-Sternberg cells in EBV positive and EBV negative Hodgkin's lymphomas, Bcl-2 positivity and evaluation of survival].

J Macák, M Bertová

Vnitr Lek 2001, 47(3):151-155

Mummified tumour cells in Hodgkin's lymphoma (HL) are a special type of programmed cellular death, which differs from apoptosis in several respects. The common feature with apoptosis is the death of individual tumour cells. The number of mummified cells is many times higher than the number of cells in apoptosis. The authors examined a group of 24 cases of EBV positive and 24 cases of EBV negative HL and assessed the so-called mummification index. The value of the mummification index was 10.4 in EBV positive and 8.2 in EBV negative HL. The difference of values was not marked and therefore it may be concluded that latent EBV infection does not influence...

[Echoccardiographic hyperventilation test in patients with negative coronarography].

E Sovová, D Marek, M Skvarilová, J Lukl

Vnitr Lek 2001, 47(3):156-159

Opportunities to examine patients with spastic angina pectoris are at present, due to the inaccessibility of ergonovine, very limited. The authors demonstrate on a small group of patients the application of echocardiographic hyperventilation test for assessment of the diagnosis of spastic angina pectoris.

[Correlation of a change in the amplitude of the R wave during ergometry with the finding of significant stenosis of the coronary artery].

R Panovský, E Petrikovits, L Groch, J Seménka

Vnitr Lek 2001, 47(3):160-165

The authors evaluated retrospectively 224 patients with ischaemic heart disease. These patients were subjected to an ergometric loading test on a bicycle ergometer followed by angiography of the coronary arteries. With regard to the site of the increased amplitude of R waves during the loading test the patients were divided into seven groups which were sub-divided further according to the coronarographic finding. The authors investigated the assumption that patients with pathological changes of R waves above the anterior wall suffer from afflictions of the ramus interventricularis anterior, patients with changes above the lateral wall of the ramus...

[Microcytic and hypochromic anemias].

L Chrobák

Vnitr Lek 2001, 47(3):166-174

In the majority of cases, microcytosis is the result of impaired hemoglobin synthesis. Disorders of iron metabolism and protoporphyrin and heme synthesis, as well as impaired globin synthesis, lead to defective hemoglobin production and to the generation of microcytosis and microcytic anemia. Iron deficiency anemie, anemia of chronic diseases, thalassemias, congenital sideroblastic anemias and homozygous HbE disease are the main representatives of microcytosis and microcytic anemias. Serum iron, total iron binding capacity, transferrin saturation, serum ferritin, serum transferrin receptor, transferrin receptor-ferritin index, and zinc-protoporhyrin...

[Cytoimunofluorometry and its use in the detection of blood platelet activation].

M Loudová, J Krejsek, O Kopecký, J Malý

Vnitr Lek 2001, 47(3):175-180

Blood platelet activation is a complex process involved in the physiological hemostasis and also in a number of disorders. Platelets change their morphology, modify their surfaces glycoprotein receptors with adhesive functions. Procoagulant microparticles are shedding and the aggregates of platelets with leucocytes are appearing. The activated platelet can be detected by flow cytometry after imunofluorescent staining.

[Hypernatraemia, increased protein intake and progression of renal insufficiency in a patient with polycystic renal degeneration].

L Nosková-Lyerová, O Viklický, O Schück

Vnitr Lek 2001, 47(3):181-184

The authors submit the case of a patient with polycystic degeneration of the kidneys where after haemorrhage from the anterior cerebral artery hypernatraemia developed and concurrently significant acceleration in the progression of renal insufficiency to failure developed. Hypernatraemia was caused by non-natrium osmotic diuresis conditioned by increased urea excretion. In chronological association with increased dietary protein intake renal insufficiency was hastened.

[Uncommon case of a giant diaphragmatic hernia in a pregnant patient].

M Senkyrík, L Husová, J Lata, F Horálek, J Neubauer

Vnitr Lek 2001, 47(3):185-189

The authors submit an uncommon case of a true leftsided posterolateral (Bochdalek) hernia with the stomach, transverse colon and spleen in the hernial sac in a 25-year-old patient. They assume that the large hernation developed as a result of rupture of an already congenitally preformed hernial opening as a result of intraabdominally increased pressure during repeated pregnancies. The authors describe effective surgical solution of the case by laparoscopy from a transabdominal approach.

[ Post-graduate education].

S Alusík

Vnitr Lek 2001, 47(3):190-191