Vnitřní lékařství, 1999 (vol. 45), issue 9
[Correction of morphology and indicators of atrial function using long-term physiologic cardiac pacing in patients with prior chronic atrioventricular dissociation or VVI pacing].
D Marek, E Sovová, M Berková, J Lukl, C Cíhalík, T Kuhn
Vnitr Lek 1999, 45(9):513-517
UNLABELLED: In patients with atrioventricular dissociation associated with complete atrioventricular block or reverse synchronization and preservation of the sinus rhythm the atria are mechanically over-burdened by contraction in an inept stage of the cardiac cycle (against a closed atrioventricular valve). Prolonged overburdening leads to dilatation of the atria and a higher incidence of supraventricular arrhythmias incl. atrial fibrillation. The objective of the trial was to assess whether these changes are reversible.METHOD: In 26 patients where atrioventricular dyssynchronization as the only detectable reason of atrial dilatation was eliminated...
[The renin-angiotensin-aldosterone system and serum lipoproteins in patients with essential hypertension].
I Lazúrová, M Pjescák, B Zábranská, D Trejbal, J Petrovicová, E Zemberová, A Kovácová
Vnitr Lek 1999, 45(9):518-521
The authors investigated the relationship between the activity of the renin-angiotensin-aldosterone system and serum lipid levels in patients with essential hypertension (EH). They examined 72 patients with EH stage I and II WHO classification (group A, n = 72, age bracket 16-70 years). They investigated the plasma renin activity (PRA), plasma aldosterone (PA) and total cholesterol (TCH), HDL, LDL cholesterol and triglycerides (TG). They divided the group into three sub-groups according to the PRA into low (L), normal (N) and high renin groups (H) In the whole group they did not find significant differences in the lipid levels in relation to PRA. They...
[Effect of long-term hypolipidemia therapy on diastolic filling of the left ventricle].
J Meluzín, V Soska, E Petrikovits, J Seménka
Vnitr Lek 1999, 45(9):522-526
In 18 patients with hypercholesterolaemia (total cholesterol > or = 6.7 mmol/l or LDL > or = 4.0 mmol/l a standard and Doppler echocardiographic examination was made before and after 27 +/- 7 months hypolipidaemic treatment leading to a drop of the cholesterol levels of at least > or = 1 mmol/l. Except for hypercholesterolaemia these patients did not suffer from any diseases with an impact on cardiac activity. Doppler echocardiography was used to measure parameters of diastolic left ventricular filling at rest and during 2-4 minutes of an isometric load. Lipid lowering therapy led to a significant drop of the deceleration half-time of early...
[Reactions to metals in patients with chronic fatigue and autoimmune endocrinopathy].
I Sterzl, P Hrdá, J Procházková, J Bártová, P Matucha
Vnitr Lek 1999, 45(9):527-531
Our study was designed to assess the effect of heavy metals on the severity of fatigue in autoimmune thyroid disease associated with autoantibodies against other endocrine organs. We compared our data with those obtained from other groups of patients. A total of five groups of patients were examined by their medical history, dental examination, and using a modified test of blast transformation of metals (Melisa): a) 10 fatigues female patients with autoimmune thyroidism and polyglandular activation of autoimmunity, b) 12 fatigued patients with autoimmune thyroidism, c) 28 fatigued patients free of endocrinopathy, d) 22 professionals without evidence...
[Basal autonomic tone in patients with vasovagal syncope].
P Mitro, D Trejbal
Vnitr Lek 1999, 45(9):532-536
Autonomic nervous mechanisms play an important part in the pathogenesis of vasovagal syncope. The objective of the submitted work was investigation of the autonomic tone in patients with vasovagal syncope. The authors examined a group of 39 patients with vasovagal syncope (patients with a positive head-up tilt test (HUT) from a group of patients with syncopes of unknown origin--12 men, 27 women, mean age 34 years), a control group of 21 patients with negative HUT from the group of patients with syncope of unknown etiology (11 men, 10 women, mean age 32 years) and a control group of 14 healthy subjects without history of syncope (14 men, mean age 26...
[Clinical aspects of Chlamydial infection].
P Hufová, V Krcová, J Lukl
Vnitr Lek 1999, 45(9):537-539
Chlamydiae are one of the most widespread pathogens of man, though up to 90% of infected people have few or no symptoms. This bacterial pathogen has been shown to cause respiratory track infections, pelvic inflammatory disease and articular diseases. We explored group of 20 patients with the elevated anti-chlamydial antibody titres and clinical significance of infection. All patients were also taking a tree-week course of antibiotics therapy.
[The effect of body weight on insulin activity].
G Sindelka, J Skrha, M Prázný, J Hilgertová
Vnitr Lek 1999, 45(9):540-544
Insulin resistance is found patients with diabetes mellitus type 2 as well as in obese subject without diabetes. The objective of our investigation was to compare the action of insulin in morbidly obese subject with and without diabetes and in diabetic subject with different degrees of obesity. A total of 36 diabetic were examined, divided according to the BMI into morbidly obese (DMTO: BMI > 40 kg/m-2.n = 6) those with medium severe obesity (DMSO: BMI 31-40 kg.m-2.n = 16), with slight overweight DMLO. BMI 26-91 kg.m-2.n = 9) and non-obese diabetics (DMBO). BMI 21-26 kg.m-2.n = 5). The group of morbidly obese non-diabetic subject (NDTO, BMI >...
[The stress ergometry test in diabetics and non-diabetics].
V Bartůnková, L Bartůněk
Vnitr Lek 1999, 45(9):545-549
OBJECTIVE: Evaluate risk factors of ischaemic heart disease (IHD) and the importance of burdening on a bicycle ergometer (BE) in the diagnosis of IHD in diabetic and non-diabetic subjects. CHARACTERISTIC OF GROUP: The authors evaluated in a retrospective study all 308 patients subjected to BE during the period 11/98-1/99 in Konstantinovy Láznĕ. Characteristics of diabetic vs. non-diabetic subjects: number (97 vs. 211), men (70.1 vs. 70.14%) mean age (59.76 vs. 58.01), height (1.71 vs. 1.71 m), body weight (85.91 vs. 81.40 kg), BMI (29.36 vs. 27.68 g/m2), total cholesterol (5.73 vs. 5.51 mmol/l,) triacylglycerols (2.63 vs. 2.08 mmol/l), fasting...
[Personal experience with therapeutic plasmapheresis using the AS.TEC 204 separator].
J Pták
Vnitr Lek 1999, 45(9):550-551
The authors experience with Fresenius AS.TEC 204 separator for therapeutic exchange plasmaphereses in patients with different diagnoses. The describe the technique of separation, evaluation of advantages of the apparatus. Minor modifications made by the author improve the process of separation. Although the apparatus does not make erythrophereses possible so far, it proved useful for exchange plasmaphereses.
[Erythema exsudativum multiforme with macroglobulinemia].
Z Churý, J Drbal, H Jedlicková, V Semrádová
Vnitr Lek 1999, 45(9):552-554
A case of a 47-year-old man with skin lesions of erythema multiforme and macroglobulinemia is reported. Histological changes corresponded with mixed dermoepidermal type of erythema multiforme and direct immunofluorescence showed fibrillar band with anti-IgM and anti-fibrin on basement membrane. Further examination revealed serum monoclonal IgM kappa with traces in urine. Association or coincidence of these findings is discussed.
[Hypertension after heart transplantation].
L Spinarová
Vnitr Lek 1999, 45(9):555-558
Transplantations of the heart are in recent years the therapeutic method in severe cardiac failure. One of the complications in the long-term follow-up of patients is the development of hypertension. The incidence of hypertension in patients treated with cyclosporin and prednisone is 70-90%. In the development of hypertension participates in addition to classical mechanisms (renin angiotensin system, fluid volume and peripheral resistance) also the negative effect of cardiac denervation, cyclosporin immunosuppression, corticoids and nephropathy. The nocturnal drop of pressure and pulse rate is lacking. Mechanisms of cyclosporin induced hypertension:enhancement...
[Hyperglycemia and atherosclerosis. Causal relation or association?].
I Tkác, V Uliciansky
Vnitr Lek 1999, 45(9):559-563
Hyperglycemia may lead to atherosclerosis by different pathogenic mechanisms. Nonenzymatic glycation and oxidation of LDL may increase its atherogenicity. Glycation may modify some arterial wall structural proteins. Increased blood glucose leads to hypertriglyceridemia which results in decrease of HDL-cholesterol level and in increase of atherogenic dense LDL particles. Hyperglycemia also adversely affects processes of platelet aggregation, hemocoagulation and fibrinolysis. It accelerates the development of diabetic nephropathy--a condition with a high prevalence of macrovascular diseases. Prospective epidemiologic studies have shown that diabetic...