Vnitřní lékařství, 1993 (vol. 39), issue 1
[Metabolic and humoral characteristics of normotensive offspring in a family with a history of essential hypertension].
K Horký, J Bultas, M Jáchymová, A Jindra, J Savlíková, J Peleska, V Umnerová, M Jarolím, P Stolba
Vnitr Lek 1993, 39(1):4-14
Investigations in genetic forms of experimental hypertensions revealed certain haemodynamic, metabolic and humoral abnormalities in experimental animals already during the prehypertensive period. With regard to the obvious ratio of hereditary factors in the pathogenesis of human essential hypertension (EH), the objective of the present study was to test whether also in healthy normotensive subjects with a positive family history of EH some metabolic and humoral deviations can be detected, as compared with offspring from normotensive families. The authors compared therefore selected biochemical and humoral parameters in 20 sons of hypertensive parents...
[Arterial hypertension in clinical practice].
J Zicha, O Pálka, P Dobes
Vnitr Lek 1993, 39(1):15-23
Based on their epidemiological survey in the South Moravian region where 64,083 men and women, mean age 43.1 years, were examined, the authors submit the results of screening, prevalence, control and complications of hypertension. They draw attention to the high rate and almost 50% detection of new patients, in particular of productive age. The results indicate the high risk of arterial hypertension in the genesis of cerebrovascular and cardiovascular disease, on the inadequate control of the disease in field practice and the favourable effect on the prevalence of cerebrovascular disease when effective therapy is used, as apparent from a five-year...
[Isolated hematuria in adolescents and adults. The value of renal biopsy].
V Monhart, J Marek, O Krenek
Vnitr Lek 1993, 39(1):24-30
In 103 subjects with asymptomatic isolated haematuria (persisting for more than 6 months in the absence of proteinuria, bacteriuria, impaired haemocoagulation or urological disease) renal biopsy was performed. The mean age of the patients was 25.2 years, range 14-58 years. In 94% glomerular changes were detected--most frequently minimal glomerular lesions (67%) and proliferative mesangial glomerulonephritis (15%). Focal segmental proliferative glomerulonephritis was rare (4%). Immunofluorescent examination revealed IgA nephropathy in 40% (all cases of diffuse and focally segmental proliferative glomerulonephritis and one quarter of minimal glomerular...
[Energy expenditure at rest in patients with active rheumatoid arthritis and malnutrition].
M Kvapil
Vnitr Lek 1993, 39(1):31-37
Malnutrition is found significantly more often in patients with rheumatoid arthritis than in the normal population. One of the contributing causes may be the elevated energy expenditure at rest found in the stage of increased activity of the disease. The aim of the present work was to evaluate the association between the activity of the disease, the presence of signs of malnutrition and the energy expenditure at rest. In 26 patients with rheumatoid arthritis stage I-IV, mean age 62.2 +/- 11.0 years the basic parameters describing the activity of the disease were assessed (sedimentation rate, C-reactive protein (CRP), the articular index according to...
[Ambulatory therapy of internal hemorrhoids using infrared photocoagulation and elastic ligature].
M Sorf, V Krislo, T Skovajsová, V Lackovicová
Vnitr Lek 1993, 39(1):38-42
The authors present their experience with infrared photocoagulation and its combination with suction ligature by means of elastic rings in the treatment of internal haemorrhoids. They used infrared photocoagulation in 15 patients with grade I haemorrhoids, the procedure was painless in 80% and 20% of the patients reported mild pain. As to side-effects, 13.3% reported mild discomfort during defaecation. After one month 66.6% were symptom-free, 26.7% improved and 6.7% did not report improvement. The authors used the combination of suction ligation and infrared photocoagulation in 27 patients with internal haemorrhoids grade II. The procedure was painless...
[What are the characteristic signs of cholecystolithiasis in patients with type 2 diabetes?].
V Růzek, T Vaněcek, M Suranová
Vnitr Lek 1993, 39(1):43-48
In a group of 166 patients with type 2 diabetes mellitus, hospitalized at the First Medical Clinic, Faculty Hospital Prague 5-Motol, cholecystolithiasis was found in 91. In these patients sonographic parameters were analyzed. All were hospitalized primarily on account of a non-biliary indications. The group comprised 67 men, mean age 69 years. The control group was formed by 67 patients with a normal glucose tolerance. An enlarged gallbladder was found in 15 patients (16.4%), a gallbladder of reduced size in 8 (8.8%). Stones smaller than 1 cm were in the group of diabetics in 31 subjects (34.3%), stones larger than 1 cm in 60 (65.7%). A wall of the...
[Determination of HLA-B27 antigen subtypes from the results of lymphocyte reactions to anti-HLA-B27 sera].
A Májský
Vnitr Lek 1993, 39(1):49-53
Forty-five specimens of lymphocytes from HLA-B27 positive subjects were examined by the micro-lymphocytotoxic test with 48 anti-HLA-B27 sera and the results were evaluated statistically by calculation of the correlation coefficient r. Based on the results of the statistical evaluation two groups of sera were determined which determined two groups of lymphocytes, carriers of different HLA-B27 subtypes. Six sera determined subtype B27P1, detected in four lymphocyte samples, another six sera subtype B27P2 found in three lymphocytes. The results of the statistical evaluation correspond to the serological reactions. The results indicate that HLA antigens...
[A rare occurrence of familial idiopathic pulmonary fibrosis].
P Václavík
Vnitr Lek 1993, 39(1):54-58
The author describes rare familial incidence of idiopathic pulmonary fibrosis. The disease occurred and was the cause of death in all three children under five years--the patient's daughters. The patient contracted the disease at the age of 59 years. When modern treatment is used, the course of the disease is so far favourable. The author discusses aetiopathogenetic and hereditary aspects of idiopathic pulmonary fibrosis. He reminds of contemporary possibilities of diagnosis of this rare but very serious pulmonary disease.
[Behçet's disease and IgG lambda paraproteinemia].
R Pudil, Z Hrncír, M Tichý, J Bures
Vnitr Lek 1993, 39(1):59-64
The authors describe the clinical observation and therapeutic experience of the seven-year follow-up of a female patient with Behcet's disease according to the diagnostic classification criteria of the International Study Group (1990). The remarkable feature of the described observation is evidence of the herpes simplex virus type I in the oral cavity and in particular the five-year follow-up of stabilized paraproteinaemia IgG lambda of obscure impact.
[Angiologic findings in type 1 diabetics who have had diabetes longer than 25 years].
A Adamíková, E Záhumenský
Vnitr Lek 1993, 39(1):65-69
The authors present a group of type 1 diabetics with duration of IDDM longer than 25 years (15 men and 10 women), mean age 53.8 years, mean duration from diagnosis of IDDM 35.0 years. The authors performed angiologic examination by using noninvasive methods with focus on affections of extracranial carotid arteries and peripheral arteries by using ultrasonographic methods and by measuring skin perfusion pressure by the photocell of the plethysmograph on the fingers of lower extremities. The authors investigated the subsequent risk factors--obesity, smoking, hypertension, hyperlipoproteinaemias, ischaemic heart disease, strokes. Macroangiopathy of lower...
[Ultrasonography in the diagnosis of lung diseases].
M Alaxinová
Vnitr Lek 1993, 39(1):70-76
Ultrasonographic examination of the chest despite limiting factors holds an important place in the diagnosis of pulmonary diseases. In the submitted paper the author describes in detail in addition to indications of ultrasonographic examination, ultrasonographic findings in pathological processes--a free and encapsulated pleural exudate, empyema, tumours of the lungs and pleura, haemothorax, atelectasis of the pulmonary parenchyma. In the ultrasonographic picture the author evaluated the echogenity of the finding, the presence of septa, fibrin fibres and spirals, the presence of different loculations. The authors reached the conclusion that, based...
[Little known paraneoplastic syndromes].
M Zuffa
Vnitr Lek 1993, 39(1):77-80
The author describes briefly some little known paraneoplastic syndromes: hypertension, circulatory failure, arterial ischaemia, Stauffer's syndrome, visceral neuropathy, thyroiditis and others. He comments on them, based on his own experience.