Vnitr Lek 2025, 71(6):E1-E12 | DOI: 10.36290/vnl.2025.075

Cardiovascular diseases in pregnancy - a current overview

Jana Čepelová
Interní klinika 1. LF UK a ÚVN, Ústřední vojenská nemocnice - Vojenská fakultní nemocnice Praha

Even though, there have been many advances in maternal medical care and fertility treatments, the presence of cardiovascular disease has a significant impact on pregnancy. Congenital heart diseases, valvular heart diseases, chronic hypertension and cardiomyopathies are linked to increased risk of maternal as well as fetal morbidity and mortality. The management of the pre-existing heart diseases in pregnancy has been challenging for cooperation of cardiologists and gynecologists, in order to improve maternal and fetal morbidity and mortality. This overview offers a summary of the recent knowledge of pregnancy-related cardiovascular diseases in women.

Keywords: cardiovascular diseases, pregnancy, pregnancy heart team, pre-pregnancy counselling, risk of maternal complications.

Accepted: September 21, 2025; Published: October 2, 2025  Show citation

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Čepelová J. Cardiovascular diseases in pregnancy - a current overview. Vnitr Lek. 2025;71(6):E1-12. doi: 10.36290/vnl.2025.075.
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    References

    1. Sahu AK, Harsha MM, Rathoor S. Cardiovascular Diseases in Pregnancy - A Brief Overview. Curr Cardiol Rev. 2022; 18(1):77-88. Go to original source... Go to PubMed...
    2. Regitz-Zagrosek V, Roos-Hesselink JW, Bauersachs J, et al. 2018 ESC Guidelines for the management of cardiovascular diseases during prenancy. Eur Heart J. 2018;39:3165-3241. Go to original source... Go to PubMed...
    3. Moťovská Z, Hutyra M, Pařenica J. Doporučení ESC pro léčbu kardiovaskulárních onemocnění v těhotenství, 2018. Cor Vasa 2019;61:e195-e236. Go to original source...
    4. Tamirisa K, Oliveros E, Paulraj S, et al. An Overview of Arrhythmias in Pregnancy. Methodist DeBakey. Cardiovasc J. 2024;20(2):36-50. Go to original source... Go to PubMed...
    5. Silversides C, Grewal J, Mason J, et al. Pregnancy outcomes in women with heart disease: The CARPREG II Study. J Am Coll Cardiol. 2018;71:2419-2430. Go to original source... Go to PubMed...
    6. Roos-Hesselink J, Baris L, Johnson M, et al. Pregnancy outcomes in women with cardiovascular disease: evolving trends over 10 years in the ESC Registry Of Pregnancy And Cardiac disease (ROPAC). Eur Heart J 2019;40:3848-3855. Go to original source... Go to PubMed...
    7. Bello NA, Merz NB, Brown H, et al. Cardio-Obstetric Part 4: Cardiovascular Diagnostic and Therapeutic Strategies in Pregnancy: JACC Focus Seminar. J Am Coll Cardiol. 2021;77(14):1813-1822. Go to original source... Go to PubMed...
    8. Assenza GE, Dimopoulos K, Budts W, et al. Management of acute cardiovascular complications in pregnancy. Eur Heart J 2021;42:4224-4240. Go to original source... Go to PubMed...
    9. Cífková R. Hypertension in pregnancy: A diagnostic and therapeutic overview. High Blood Presure and Cardiovascular Prevention 2023;30:289-303. Go to original source... Go to PubMed...
    10. Parikh NI, Gonzalez JM, Anderson Ch, et al. Adverse Pregnancy Outcomes and Cardiovascular Disease Risk: Unique Opportunities for Cardiovascular Disease Prevention in Women. Circulation 2021;143:e902-e916. Go to original source... Go to PubMed...
    11. Ives CW, Sinkey R, Rajapreyar I, et al. Preeclampsia - Pathophysiology and Clinical Presentations. J Am Coll Cardiol. 2020;76:1690-702. Go to original source... Go to PubMed...
    12. Cameron NA, Everitt IK, Lee KA, et al. Chronic Hypertension in Pregnancy: A Lens into Cardiovascular Disease Risk and Prevention. Hypertension 2023;80(6):1162-1170. Go to original source... Go to PubMed...
    13. Sukmanee J, Liabsuetrakul T. Risk of future cardiovascular diseases in different years postpartum after hypertensive disorders of pregnancy. Medicine 2022;101(30):1-13. Go to original source... Go to PubMed...
    14. Schaufelberger M. Cardiomyopathy and pregnancy. Heart. 2019;105:1543-1551. Go to original source... Go to PubMed...
    15. Garovic V, Dechend R, Easterling T, et al. Hypertension in Pregnancy: Diagnosis, Blood Presure Goals and Pharmacotherapy: A Scientific Statement From the American Heart Association. Hypertension 2022;79:e21-e41. Go to original source... Go to PubMed...
    16. Siu SC, Sermer M, Colman JM, et al. Prospective multicenter study of pregnancy outcomes in women with heart disease. Circulation 2001;104(5):515-21. Go to original source... Go to PubMed...
    17. Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA Guideline for the management of patients with valvular heart disease: Executive Summary: A report of the American College of Cardiology/American Heart Assotiation joint committee on clinical practice guidelines. Circulation 2021;143(5):e35-71. Go to original source... Go to PubMed...
    18. Arif AF, J Women Health Gynecol Res. 2021:1(1):202.

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